Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils.

Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Research Abstract Details 

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Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Abstract Text:

D J Rivet,C J Moran,A Mazumdar,T K Pilgram,C P Derdeyn,D T Cross,D J Rivet,C J Moran,A Mazumdar,T K Pilgram,C P Derdeyn,D T Cross,D J Rivet,C J Moran,A Mazumdar,T K Pilgram,C P Derdeyn,D T Cross,

BACKGROUND AND PURPOSE: This study was undertaken to analyze the outcomes and treatment-related complications of the polyglycolic/polylactic acid (PGLA)-coated Matrix platinum coils in the treatment of intracranial aneurysms and compare these results with those derived from the same single-institutional experience with use of uncoated, bare platinum coils. MATERIALS AND METHODS: In this study, we compared 2 groups of patients in a retrospective fashion. The first group consisted of 70 consecutive patients who underwent 82 aneurysm treatments with Matrix coils during the 14-month period of study, from January 2003 to February 2004. We compared this cohort with 70 consecutive patients who underwent a total of 80 aneurysm treatments with bare platinum coils in the 12 months immediately preceding the use of PGLA-coated coils, from January through December 2002. We then recorded the treatment characteristics, angiographic outcomes, and any complications. RESULTS: There were similar baseline demographic characteristics between the 2 study groups except in age, anatomic location, and length of follow-up. The overall recurrence rate of aneurysms was 41% among the Matrix-treated group and 32% among the patients treated with bare platinum. Among the 42 patients treated with 100% Matrix, the rate of recurrence was 31%. Of the recurrences, 21% of the Matrix group, 19% of the 100% Matrix group, and 9% of the bare platinum group required retreatment. The overall rate of complications was 10% in the Matrix-treated group and 7% in the bare platinum group. There was not a statistically significant difference in the rate of recurrence of aneurysms or complications between the 2 groups. CONCLUSIONS: On the basis of our single-center experience, there is insufficient evidence to support the use of Matrix coils over bare platinum coils, given their disadvantages.

Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Publishing Authors By Initials

DJ Rivet,CJ Moran,A Mazumdar,TK Pilgram,CP Derdeyn,DT Cross,DJ Rivet,CJ Moran,A Mazumdar,TK Pilgram,CP Derdeyn,DT Cross,DJ Rivet,CJ Moran,A Mazumdar,TK Pilgram,CP Derdeyn,DT Cross,

For similar diagnosis: prognosis: treatment outcome research abstracts see: diagnosis: prognosis: treatment outcome research

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Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJNR. American journal of neuroradiology

VOLUME: 28

Page Numbers: 1736-42

Journal Abbreviation:

ISSN: 0195-6108

DAY: 20

MONTH: 09

YEAR: 2007

Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Information

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LANGUAGE: eng

NlmUniqueID: 8003708

Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Keywords Mesh Terms:

KEYWORDS: Treatment Outcome

MESH TERMS: prevention & control

Chemical & Substance for Abstract: Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils. Information

Substance Name: Platinum

Registry Number: 7440-06-4

Grant and Affiliation Information for Single-institution experience with matrix coils in the treatment of intracranial aneurysms: comparison with same-center outcomes with the use of platinum coils.

AFFILIATION: Neuroradiology Section, Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA. dennis.rivet@med.navy.mil

Country: United States

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MEDLINETA: AJNR Am J Neuroradiol

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