Silylative Dieckmann-like cyclizations of ester-imides (and diesters).

Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Research Abstract Details 

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Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Abstract Text:

Thomas R Hoye,Vadims Dvornikovs,Elena Sizova,

[Structure: see text] Trialkylsilyl triflates effect cyclization of ester-imides such as 2 to produce adducts such as 4a. Trapping of the in situ generated, nucleophilic ketene acetal (cf. 5a) is a key aspect of the transformation. A range of substrates amenable to this operationally simple reaction is reported. In many instances the levels of diastereoselectivity are very high. Mechanistic points are inferred from spectroscopic observations.

Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Publishing Authors By Initials

TR Hoye,V Dvornikovs,E Sizova,

For similar heterocyclic compounds: alkaloids: pyrrolizidine alkaloids research abstracts see: heterocyclic compounds: alkaloids: pyrrolizidine alkaloids research

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Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Organic letters

VOLUME: 8

Page Numbers: 5191-4

Journal Abbreviation: Org. Lett.

ISSN: 1523-7060

DAY: 9

MONTH: Nov

YEAR: 2006

Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100890393

Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Keywords Mesh Terms:

KEYWORDS: Pyrrolizidine Alkaloids

MESH TERMS: chemistry

Chemical & Substance for Abstract: Silylative Dieckmann-like cyclizations of ester-imides (and diesters). Information

Substance Name: UCS 1025A

Registry Number: 0

Grant and Affiliation Information for Silylative Dieckmann-like cyclizations of ester-imides (and diesters).

AFFILIATION: Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, USA. hoye@chem.umn.edu

Country: United States

AGENCY: United States NIGMS

GRANT: GM-65597

ACRONYM: GM

MEDLINETA: Org Lett

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