Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients.

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Abstract Text:

E Ishimura,S Okuno,K Kitatani,T Tsuchida,T Yamakawa,A Shioi,M Inaba,Y Nishizawa,E Ishimura,S Okuno,K Kitatani,T Tsuchida,T Yamakawa,A Shioi,M Inaba,Y Nishizawa,

AIM: Vascular calcification, which significantly increases cardiovascular and other causes of mortality, is highly prevalent in hemodialysis patients. The aim of the present study was to examine the association between serum magnesium levels and vascular calcification in hemodialysis patients. METHODS: 390 nondiabetic patients on maintenance hemodialysis (226 males and 164 females, 59 +/- 13 years) were examined. Hand roentgenography was performed in each patient, and visible vascular calcification of the hand arteries was evaluated. Blood was drawn to measure serum calcium, phosphate, magnesium and intact parathyroid hormone levels. RESULTS: There were 52 patients (38 males and 14 females) with vascular calcification, and 338 (188 males and 150 females) without. Serum phosphate was significantly higher in the former compared with the latter group (p < 0.005); serum intact parathyroid hormone was significantly higher (p < 0.05), whereas serum calcium was not statistically different between the two groups. Serum magnesium was significantly lower in patients with vascular calcification than in those without (2.69 +/- 0.28 vs. 2.78 +/- 0.33 mg/dl, p < 0.05). Multivariate logistic regression analysis revealed that serum magnesium concentration was a significant independent factor associated with the presence of vascular calcification in hemodialysis patients (odds ratio 0.28, 95% CI 0.09 - 0.92/1 mg/dl increase in serum magnesium, p = 0.036) after adjustment for age, gender, duration of hemodialysis, calcium, phosphate and intact parathyroid hormone concentrations. CONCLUSION: Hypomagnesemia is significantly associated with the presence of vascular calcification of the hand arteries, independent of serum calcium and phosphate levels. These results suggest that higher serum magnesium concentrations may play an important protective role in the development of vascular calcification in hemodialysis patients, and that magnesium concentration of dialysis fluid may be reconsidered in view of preventing vascular calcification in hemodialysis patients.

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Publishing Authors By Initials

E Ishimura,S Okuno,K Kitatani,T Tsuchida,T Yamakawa,A Shioi,M Inaba,Y Nishizawa,E Ishimura,S Okuno,K Kitatani,T Tsuchida,T Yamakawa,A Shioi,M Inaba,Y Nishizawa,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nephrology

VOLUME: 68

Page Numbers: 222-7

Journal Abbreviation: Clin. Nephrol.

ISSN: 0301-0430

DAY: 30

MONTH: Oct

YEAR: 2007

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 364441

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients.

AFFILIATION: Department of Nephrology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. ish@med.osaka-cu.ac.jp

Country: Germany

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Clin Nephrol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients Related Publications

• A possible variant of neuro-Behçet disease presenting chronic progressive ataxia without mucocutaneo-ocular symptoms.
• Bladder-sparing extended resection of locally advanced rectal cancer involving the prostate and seminal vesicles.
• Body fat measurement in chronic kidney disease: implications in research and clinical practice.
• Changes in brachial-ankle pulse wave velocity in subclinical hypothyroidism during normalization of thyroid function.
• Chronic myositis with cardiomyopathy and respiratory failure associated with mild form of organ-specific autoimmune diseases.
• Clinical features of patients with myasthenia gravis associated with autoimmune diseases.
• Clinical impact of metabolic syndrome by modified NCEP-ATPIII criteria on carotid atherosclerosis in Japanese adults.
• Establishment of a progesterone-sensitive cell line from human lung cancer.
• Expression and enzyme activity of glutathione reductase is upregulated by Fe-deficiency in graminaceous plants.
• Fine structure of laminaran of Eisenia bicyclis.
• Floridean starch of a calcareous red alga, Joculator maximus.
• Generation of patterned cell co-cultures in silicone tubing using a microelectrode technique and electrostatic assembly.
• Heterogeneity of alginate in special reference to the enzymatic degradation.
• Identification and localisation of the rice nicotianamine aminotransferase gene OsNAAT1 expression suggests the site of phytosiderophore synthesis in rice.
• In situ control of cellular growth and migration on substrates using microelectrodes.
• Natural history and etiology of high pressure voiding in male infants.
• Overexpression of the OsZIP4 zinc transporter confers disarrangement of zinc distribution in rice plants.
• Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism.
• RAGE and Soluble RAGE: Potential Therapeutic Targets for Cardiovascular Diseases.
• Regulatory mechanisms of circulating fibroblast growth factor 23 in parathyroid diseases.
• Retrieving reflection responses by crosscorrelating transmission responses from deterministic transient sources: Application to ultrasonic data.
• Sacsin-related ataxia with neither retinal hypermyelination nor spasticity.
• Significance of thyroid blood flow as a predictor of methimazole sensitivity in untreated hyperthyroid patients with Graves' disease.
• Significant association between the presence of peripheral vascular calcification and lower serum magnesium in hemodialysis patients.
• Stepwise formation of patterned cell co-cultures in silicone tubing.
• The rice bHLH protein OsIRO2 is an essential regulator of the genes involved in Fe uptake under Fe-deficient conditions.
• [Examination of influence on atherosclerosis with the improvement of bone mineral density after medication for osteoporosis]
• [Mutational reconstructed ferric chelate reductase confers enhanced tolerance in rice to iron deficiency in calcareous soil]
• [Outline of guideline 2004 for bone marker in osteoporosis]
• [P1NP]