Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum.

Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Research Abstract Details 

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Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Abstract Text:

Emily A Dertz,Alain Stintzi,Kenneth N Raymond,

Hexadentate bacillibactin is the siderophore of Bacillus subtilis and is structurally similar to the better known enterobactin of Gram-negative bacteria such as Escherichia coli. Although both are triscatecholamide trilactones, the structural differences of these two siderophores result in opposite metal chiralities, different affinity for ferric ion, and dissimilar iron transport behaviors. Bacillibactin was first reported as isolated from Corynebacterium glutamicum and called corynebactin. However, failure of iron-starved C. glutamicum to transport 55Fe bacillibactin and lack of required bacillibactin biosynthetic genes suggest that bacillibactin is not the siderophore produced by this organism. Iron transport mediated by siderophores in B. subtilis occurs through a transport process that is specific for the iron chelating moiety, with parallel pathways for catecholates and hydroxamates. For bacillibactin, enterobactin, and their analogs, neither chirality nor presence of an amino acid spacer affects the uptake and transport process, but alteration of the net charge and size of the molecule impedes the recognition.

Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Publishing Authors By Initials

EA Dertz,A Stintzi,KN Raymond,

For similar natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research abstracts see: natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research

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Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of biological inorganic chemistry : JBIC :

VOLUME: 11

Page Numbers: 1087-97

Journal Abbreviation: J. Biol. Inorg. Chem.

ISSN: 0949-8257

DAY: 16

MONTH: 08

YEAR: 2006

Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9616326

Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Keywords Mesh Terms:

KEYWORDS: Stereoisomerism

MESH TERMS: metabolism

Chemical & Substance for Abstract: Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum. Information

Substance Name: Iron

Registry Number: 7439-89-6

Grant and Affiliation Information for Siderophore-mediated iron transport in Bacillus subtilis and Corynebacterium glutamicum.

AFFILIATION: Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720-1460, USA. edertz@hsph.harvard.edu

Country: Germany

AGENCY: United States NIAID

GRANT: AI 11744

ACRONYM: AI

MEDLINETA: J Biol Inorg Chem

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