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Side effects of diphtheria-tetanus toxoid in adults.

Side effects of diphtheria-tetanus toxoid in adults. Research Abstract Details 

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  • Side effects of diphtheria-tetanus toxoid in adults. Abstract Text:

    j p middaughJ P Middaugh,

    During a mass diphtheria-tetanus immunization campaign in November 1975, more than 220,000 doses of diphtheria-tetanus toxoid, adult type were administered to adults throughout Alaska. In Anchorage, where more than 87,000 doses were given, a survey was conducted to determine the frequency of side effects. Postcard questionnaires were mailed to 2,000 randomly selected Anchorage residents; 467 questionnaires were returned by the post office as undeliverable, and 697 questionnaires were completed and returned. A follow-up survey was done of a random sample of the 836 non-responders.Of those responding, 57.8 per cent reported at least one reaction to the toxoids. The most frequent side effects were sore arm (42.7 per cent), swelling at the site of injection (34.8 per cent), and itching (24.2 per cent). Serious side effects occurred less frequently-swelling of the arm below the elbow (1.1 per cent) and abscess or infection (0.7 per cent). Of those vaccinated, 0.5 per cent saw a physician. There were no statistically significant differences in reaction rates by age group, except for sore arms. The jet injector produced more arm swelling at the site of injection, hives, and itching. More women than men reported adverse reactions, especially sore arm, swelling at the site of injection, and itching. Fear of adverse side effects should not preclude mass vaccination of adults. (Am. J. Public Health (69:246-249,1979.)

    Side effects of diphtheria-tetanus toxoid in adults. Publishing Authors By Initials

    jp middaughJP Middaugh,

    For similar therapeutics: biological therapy: immunotherapy: immunization: immunotherapy, active: vaccination research abstracts see: therapeutics: biological therapy: immunotherapy: immunization: immunotherapy, active: vaccination research

    PUBMED ID PMID:

    MEDLINE DATE:

    Side effects of diphtheria-tetanus toxoid in adults. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: American journal of public health

    VOLUME: 69

    Page Numbers: 246-9

    Journal Abbreviation:

    ISSN: 0090-0036

    DAY: 11

    MONTH: Mar

    YEAR: 1979

    Side effects of diphtheria-tetanus toxoid in adults. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 1254074

    Side effects of diphtheria-tetanus toxoid in adults. Keywords Mesh Terms:

    KEYWORDS: Vaccination

    MESH TERMS: adverse effects

    Chemical & Substance for Abstract: Side effects of diphtheria-tetanus toxoid in adults. Information

    Substance Name: Tetanus Toxoid

    Registry Number: 0

    Grant and Affiliation Information for Side effects of diphtheria-tetanus toxoid in adults.

    AFFILIATION:

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Am J Public Health

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    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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