Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France.

Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Research Abstract Details 

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Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Abstract Text:

Laurent Argaud,Tristan Ferry,Quoc-Hung Le, Marfisi,Diana Ciorba,Pierre Achache,Roland Ducluzeau,Dominique Robert,Laurent Argaud,Tristan Ferry,Quoc-Hung Le, Marfisi,Diana Ciorba,Pierre Achache,Roland Ducluzeau,Dominique Robert,

BACKGROUND: During August 2003, Europe sustained a severe heat wave that resulted in 14 800 heat-related deaths in France. Most of these excess deaths occurred in urban areas, where maximal temperatures broke all records. Heatstroke is the most severe form of heat-related illness. The clinical course of heatstroke in urban areas of temperate countries is poorly documented. METHODS: During the French heat wave (August 1-20, 2003), we conducted a prospective study in a university hospital located in Lyon, one of the largest metropolitan areas in France. We evaluated survival and functional outcome for 2 years and looked for factors influencing the prognosis. RESULTS: A total of 83 patients presented with heatstroke. The 28-day and 2-year mortality rates were 58% and 71%, respectively. Mortality was influenced as early as admission by the level of fever and the number of organ dysfunctions. Multivariate analysis revealed an independent contribution to mortality if patients came from an institution (hazard ratio [HR], 1.98; 95% confidence interval [CI], 1.05-3.71), used long-term antihypertensive medication (HR, 2.17; 95% CI, 1.17-4.05), or presented at admission with anuria (HR, 5.24; 95% CI, 2.29-12.03), coma (HR, 2.95; 95% CI, 1.26-6.91), or cardiovascular failure (HR, 2.43; 95% CI, 1.14-5.17). Most surviving patients exhibited a dramatic alteration of their functional status at 1 and 2 years. CONCLUSIONS: Heatstroke is associated with poor outcomes in temperate urban areas. This could be explained at least in part by our lack of experience. Western temperate countries need to be more prepared for future heat waves.

Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Publishing Authors By Initials

L Argaud,T Ferry,QH Le,A Marfisi,D Ciorba,P Achache,R Ducluzeau,D Robert,L Argaud,T Ferry,QH Le,A Marfisi,D Ciorba,P Achache,R Ducluzeau,D Robert,

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Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of internal medicine

VOLUME: 167

Page Numbers: 2177-83

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ISSN: 0003-9926

DAY: 13

MONTH: 08

YEAR: 2007

Short- and long-term outcomes of heatstroke following the 2003 heat wave in Lyon, France. Information

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LANGUAGE: eng

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AFFILIATION: Service de Réanimation Médicale, Groupement Hospitalier Edouard Herriot, 5 Place d'Arsonval, Lyon CEDEX 03, France. laurent.argaud@chu-lyon.fr

Country: United States

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MEDLINETA: Arch Intern Med

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