Shielding design for a laser-accelerated proton therapy system.

Shielding design for a laser-accelerated proton therapy system. Research Abstract Details 

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Shielding design for a laser-accelerated proton therapy system. Abstract Text:

J Fan,W Luo,E Fourkal,T Lin,J Li,I Veltchev,C-M Ma,

In this paper, we present the shielding analysis to determine the necessary neutron and photon shielding for a laser-accelerated proton therapy system. Laser-accelerated protons coming out of a solid high-density target have broad energy and angular spectra leading to dose distributions that cannot be directly used for therapeutic applications. A special particle selection and collimation device is needed to generate desired proton beams for energy- and intensity-modulated proton therapy. A great number of unwanted protons and even more electrons as a side-product of laser acceleration have to be stopped by collimation devices and shielding walls, posing a challenge in radiation shielding. Parameters of primary particles resulting from the laser-target interaction have been investigated by particle-in-cell simulations, which predicted energy spectra with 300 MeV maximum energy for protons and 270 MeV for electrons at a laser intensity of 2 x 10(21) W cm(-2). Monte Carlo simulations using FLUKA have been performed to design the collimators and shielding walls inside the treatment gantry, which consist of stainless steel, tungsten, polyethylene and lead. A composite primary collimator was designed to effectively reduce high-energy neutron production since their highly penetrating nature makes shielding very difficult. The necessary shielding for the treatment gantry was carefully studied to meet the criteria of head leakage <0.1% of therapeutic absorbed dose. A layer of polyethylene enclosing the whole particle selection and collimation device was used to shield neutrons and an outer layer of lead was used to reduce photon dose from neutron capture and electron bremsstrahlung. It is shown that the two-layer shielding design with 10-12 cm thick polyethylene and 4 cm thick lead can effectively absorb the unwanted particles to meet the shielding requirements.

Shielding design for a laser-accelerated proton therapy system. Publishing Authors By Initials

J Fan,W Luo,E Fourkal,T Lin,J Li,I Veltchev,CM Ma,

For similar therapeutics: radiotherapy: radiotherapy, high-energy research abstracts see: therapeutics: radiotherapy: radiotherapy, high-energy research

PUBMED ID PMID:

MEDLINE DATE:

Shielding design for a laser-accelerated proton therapy system. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Physics in medicine and biology

VOLUME: 52

Page Numbers: 3913-30

Journal Abbreviation:

ISSN: 0031-9155

DAY: 6

MONTH: 06

YEAR: 2007

Shielding design for a laser-accelerated proton therapy system. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 401220

Shielding design for a laser-accelerated proton therapy system. Keywords Mesh Terms:

KEYWORDS: Radiotherapy, High-Energy

MESH TERMS: instrumentation

Chemical & Substance for Abstract: Shielding design for a laser-accelerated proton therapy system. Information

Substance Name: Protons

Registry Number: 0

Grant and Affiliation Information for Shielding design for a laser-accelerated proton therapy system.

AFFILIATION: Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

Country: England

AGENCY: United States NCI

GRANT: CA78331

ACRONYM: CA

MEDLINETA: Phys Med Biol

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