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Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae.

Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Research Abstract Details 

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  • Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Abstract Text:

    austin l hughesAustin L Hughes,robert friedmanRobert Friedman,

    In a set of 190 duplicate gene pairs in yeast Saccharomyces cerevisiae, the sharing of transcription factors tended to decrease with increased divergence in coding sequence, at both synonymous and nonsynonymous sites. Our results showed a significantly higher sharing of transcription factors by duplicated gene pairs falling within duplicated genomic blocks than in other duplicated gene pairs; and genes in duplicated blocks also showed significantly greater conservation at the coding sequence level. In spite of the overall trends, there were certain gene pairs, both in duplicated blocks and in other genomic regions, which were highly divergent in coding sequence and yet had identical patterns of transcription factor binding. These results suggest that functional differentiation of genes after duplication is a multi-dimensional process, with different duplicate pairs differentiating in different ways.

    Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Publishing Authors By Initials

    al hughesAL Hughes,r friedmanR Friedman,

    For similar genetic phenomena: variation (genetics) research abstracts see: genetic phenomena: variation (genetics) research

    PUBMED ID PMID:

    MEDLINE DATE:

    Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Journal Published:

    PUBLICATION TYPE: Research Support, N.I.H., Extr

    Journal: Genetica

    VOLUME: 129

    Page Numbers: 301-8

    Journal Abbreviation: Genetica

    ISSN: 0016-6707

    DAY: 4

    MONTH: 08

    YEAR: 2006

    Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370740

    Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Keywords Mesh Terms:

    KEYWORDS: Variation (Genetics)

    MESH TERMS: genetics

    Chemical & Substance for Abstract: Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae. Information

    Substance Name: Transcription Factors

    Registry Number: 0

    Grant and Affiliation Information for Sharing of transcription factors after gene duplication in the yeast Saccharomyces cerevisiae.

    AFFILIATION: Department of Biological Sciences, University of South Carolina, Coker Life Sciences Bldg. 700 Sumter St., Columbia, SC 29208, USA. austin@biol.sc.edu

    Country: Netherlands

    Netherlands Research PublicationNetherlands Research Publication

    AGENCY: United States NIGMS

    GRANT: GM43940

    ACRONYM: GM

    MEDLINETA: Genetica

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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