Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor.

Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor. Research Abstract Details 

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Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor. Abstract Text:

Deborah J Walder,Terese L C Andersson,Amanda L McMillan,S Marc Breedlove,Elaine F Walker,

The 2nd to 4th finger digit ratio (2D:4D) is a sexually dimorphic feature determined during gestation indexing prenatal androgen/estrogen levels. More 'feminized' 2D:4D phenotype has been demonstrated in schizophrenia versus same-sex controls. This study examined 2D:4D in adolescents with schizotypal personality disorder (SPD). Among normal controls, right 2D:4D was significantly greater (more feminized) in females than males. We replicated laterality effects; significant sex differences only on right. There were no significant sex differences among SPDs. Diagnostic group differences were restricted to White/Caucasian males with greater right 2D:4D in SPDs. Findings suggest disruptions in prenatal gonadal hormones in vulnerability for schizophrenia.

Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor. Publishing Authors By Initials

DJ Walder,TL Andersson,AL McMillan,SM Breedlove,EF Walker,

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Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Schizophrenia research

VOLUME: 86

Page Numbers: 118-22

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ISSN: 0920-9964

DAY: 27

MONTH: 06

YEAR: 2006

Sex differences in digit ratio (2D:4D) are disrupted in adolescents with schizotypal personality disorder: altered prenatal gonadal hormone levels as a risk factor. Information

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LANGUAGE: eng

NlmUniqueID: 8804207

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AFFILIATION: Psychology Department at Brooklyn College-City University of New York, Brooklyn, NY 11210, USA. dwalder@brooklyn.cuny.edu

Country: Netherlands

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MEDLINETA: Schizophr Res

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