Sex, AGility, and the regulation of alternative splicing.

Sex, AGility, and the regulation of alternative splicing. Research Abstract Details 

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Sex, AGility, and the regulation of alternative splicing. Abstract Text:

Alternative splicing is an important means of regulating the expression of eukaryotic genes and enhancing protein diversity. A detailed examination of the Drosophila Sex-lethal gene has led to two significant discoveries-the role of the splicing factor SPF45 in defining the site of exon ligation, and that alternative splicing can be regulated at the second step.

Sex, AGility, and the regulation of alternative splicing. Publishing Authors By Initials

For similar genetic processes: sex determination (genetics) research abstracts see: genetic processes: sex determination (genetics) research

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Sex, AGility, and the regulation of alternative splicing. Journal Published:

PUBLICATION TYPE: Review

Journal: Cell

VOLUME: 109

Page Numbers: 409-12

Journal Abbreviation: Cell

ISSN: 0092-8674

DAY: 17

MONTH: May

YEAR: 2002

Sex, AGility, and the regulation of alternative splicing. Information

Number of References: 20

LANGUAGE: eng

NlmUniqueID: 413066

Sex, AGility, and the regulation of alternative splicing. Keywords Mesh Terms:

KEYWORDS: Sex Determination (Genetics)

MESH TERMS: genetics

Chemical & Substance for Abstract: Sex, AGility, and the regulation of alternative splicing. Information

Substance Name: Sxl protein, Drosophila

Registry Number: 0

Grant and Affiliation Information for Sex, AGility, and the regulation of alternative splicing.

AFFILIATION: Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington 06030, USA. graveley@neuron.uchc.edu

Country: United States

AGENCY: United States NIGMS

GRANT: R01 GM062516-01

ACRONYM: GM

MEDLINETA: Cell

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Sex, AGility, and the regulation of alternative splicing Related Publications

• A computational and experimental approach toward a priori identification of alternatively spliced exons.
• A protein interaction domain contacts RNA in the prespliceosome.
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• Exon-specific RNA interference: a tool to determine the functional relevance of proteins encoded by alternatively spliced mRNAs.
• Getting the message out.
• Identification of alternative splicing regulators by RNA interference in Drosophila.
• Molecular biology: power sequencing.
• RNA interference of mRNA processing factors in Drosophila S2 cells.
• RS domains contact the pre-mRNA throughout spliceosome assembly.
• Sex, AGility, and the regulation of alternative splicing.
• Small molecule control of pre-mRNA splicing.
• The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians.
• The haplo-spliceo-transcriptome: common variations in alternative splicing in the human population.
• The origins and implications of Aluternative splicing.
• Using single-strand conformational polymorphism gel electrophoresis to analyze mutually exclusive alternative splicing.