In this study, we investigated the effects of early postnatal sibling deprivation (EPSD) on spatial learning and memory in adult rats. Litters were culled to one pup with its mother on postnatal day (PN) 1 or 7 and their spatial learning and memory ability were examined with Morris water maze in adult. EPSD on PN1 improved, but on PN7 impaired performance of the spatial learning task in adult female rats. However, EPSD did not have any effect on the spatial learning ability in adult male rats.
Sex- and age-dependent effects of early postnatal sibling deprivation on spatial learning and memory in adult rats. Publishing Authors By Initials
Sex- and age-dependent effects of early postnatal sibling deprivation on spatial learning and memory in adult rats. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Behavioural brain research
VOLUME: 186
Page Numbers: 138-42
Journal Abbreviation: Behav. Brain Res.
ISSN: 0166-4328
DAY: 27
MONTH: 07
YEAR: 2007
Sex- and age-dependent effects of early postnatal sibling deprivation on spatial learning and memory in adult rats. Information
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LANGUAGE: eng
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AFFILIATION: National Institute on Drug Dependence, Peking University, Beijing 100083, China.
Country: Netherlands
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MEDLINETA: Behav Brain Res
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