Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations.

Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Research Abstract Details 

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Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Abstract Text:

M K Horwitt,W H Elliott,P Kanjananggulpan,C D Fitch,

The rat-fetal-resorption test currently is used to assess the biological activity of vitamin E compounds. Previous studies in humans, however, suggest that rat assays underestimate the potency of free tocopherol relative to the acetate ester form and of RRR-alpha-tocopheryl acetate relative to all-rac-alpha-tocopheryl acetate. Therefore, we studied the serum concentrations of alpha-tocopherol after ingestion of RRR-alpha-tocopheryl acetate, all-rac-alpha-tocopheryl acetate, RRR-alpha-tocopherol, RRR-alpha-tocopheryl succinate, and RRR-alpha-tocopheryl acetate plus apple pectin by each of 20 adult human subjects. Measurements were made at 0, 8, 24, and 48 h after ingestion of 800 IU of the various preparations. The results at 24 h were representative of the differences observed. The mean increase in concentration of alpha-tocopherols (mg/g lipid) in 24 h was 71.2% after RRR-alpha-tocopherol, 63.3% after RRR-alpha-tocopherol acetate, and 41.2% after RRR-alpha-tocopherol succinate. Animal assay data do not correlate with data from studies of absorption and retention in serum of alpha-tocopherols ingested by humans.

Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Publishing Authors By Initials

MK Horwitt,WH Elliott,P Kanjananggulpan,CD Fitch,

For similar heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e: tocopherols: alpha-tocopherol research abstracts see: heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e: tocopherols: alpha-tocopherol research

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Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: The American journal of clinical nutrition

VOLUME: 40

Page Numbers: 240-5

Journal Abbreviation: Am. J. Clin. Nutr.

ISSN: 0002-9165

DAY: 19

MONTH: Aug

YEAR: 1984

Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376027

Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Keywords Mesh Terms:

KEYWORDS: alpha-Tocopherol

MESH TERMS: analogs & derivatives

Chemical & Substance for Abstract: Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations. Information

Substance Name: tocopherol acetate

Registry Number: 7695-91-2

Grant and Affiliation Information for Serum concentrations of alpha-tocopherol after ingestion of various vitamin E preparations.

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Country: UNITED STATES

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MEDLINETA: Am J Clin Nutr

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