Serum antibody decay in adults following natural respiratory syncytial virus infection.

Serum antibody decay in adults following natural respiratory syncytial virus infection. Research Abstract Details 

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Serum antibody decay in adults following natural respiratory syncytial virus infection. Abstract Text:

Ann R Falsey,Harjot K Singh,Edward E Walsh,

Serum antibody decay following RSV infection in adults was examined to evaluate the durability of the immune response. Twenty subjects with RSV infection and 10 subjects who remained RSV uninfected had blood samples obtained over 16-25 months analyzed by microneutralization assay and enzyme immunoassay. The mean titers of infected subjects rose approximately eightfold post-infection. The mean rate of antibody decline was -0.20 log 2 titer per month which led to a > or =fourfold drop in titer in 75% of subjects at 1 year. In contrast, titers of uninfected subjects were relatively stable. The partial immunity resulting from a boost in serum antibody following natural RSV infection in adults appears to be short lived.

Serum antibody decay in adults following natural respiratory syncytial virus infection. Publishing Authors By Initials

AR Falsey,HK Singh,EE Walsh,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

PUBMED ID PMID:

MEDLINE DATE:

Serum antibody decay in adults following natural respiratory syncytial virus infection. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of medical virology

VOLUME: 78

Page Numbers: 1493-7

Journal Abbreviation: J. Med. Virol.

ISSN: 0146-6615

DAY: 3

MONTH: Nov

YEAR: 2006

Serum antibody decay in adults following natural respiratory syncytial virus infection. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7705876

Serum antibody decay in adults following natural respiratory syncytial virus infection. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: immunology

Chemical & Substance for Abstract: Serum antibody decay in adults following natural respiratory syncytial virus infection. Information

Substance Name: Antibodies, Viral

Registry Number: 0

Grant and Affiliation Information for Serum antibody decay in adults following natural respiratory syncytial virus infection.

AFFILIATION: Department of Medicine at Rochester General Hospital, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA. ann.falsey@viahealth.org

Country: United States

AGENCY: United States NIAID

GRANT: R01-AI-45969

ACRONYM: AI

MEDLINETA: J Med Virol

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