Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis.

Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Research Abstract Details 

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Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Abstract Text:

H Mori,M Onji,A Yoshida,R Fukunishi,

The patient was a 60-year-old Japanese male. He complained of epigastralgia and right chest pain of 4 month's duration, and general malaise, nausea and vomiting of 2 month's duration. Physical examination revealed on the right third rib a tender mass with a diameter of 2 cm and hepatomegaly with a multi-nodular surface and red palms. There were no signs of carcinoid syndrome, such as cutaneous flushing. Laboratory examinations disclosed certain biochemical alterations; alkaline phosphatase 810 IU/l, gamma-glutamyl transpeptidase (gamma-GTP) 2090 IU/l, carcinoembryonic antigen (CEA) 23.5 ng/ml and alpha-fetoprotein (AFP) 6,800 ng/ml. Both HBs-Ag and HBs-Ab were negative. The patient died in a uremic state, with rapid increases of jaundice and ascites. Autopsy revealed gastric carcinoid with extensive metastases to the liver and the bone marrow. Tumor cells showed argyrophilia but not argentaffinity. Immunofluorescence specific for AFP was positive in the hepatocytes, particularly those adjacent to the metastatic tumor cells but not in the tumor cells, either primary or secondary. 79 cases reported in Japan of serum AFP-positive malignant tumor other than hepatocellular carcinoma and certain other malignancies of germ cell origin are reviewed and discussed.

Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Publishing Authors By Initials

H Mori,M Onji,A Yoshida,R Fukunishi,

For similar proteins: fetal proteins: alpha-fetoproteins research abstracts see: proteins: fetal proteins: alpha-fetoproteins research

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Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Virchows Archiv. A, Pathological anatomy and histo

VOLUME: 387

Page Numbers: 107-16

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ISSN: 0340-1227

DAY: 20

MONTH: 02

YEAR: 1980

Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Information

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LANGUAGE: eng

NlmUniqueID: 7505137

Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Keywords Mesh Terms:

KEYWORDS: alpha-Fetoproteins

MESH TERMS: analysis

Chemical & Substance for Abstract: Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis. Information

Substance Name: alpha-Fetoproteins

Registry Number: 0

Grant and Affiliation Information for Serum alpha-fetoprotein-positive gastric carcinoid with liver metastasis.

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Country: GERMANY, WEST

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MEDLINETA: Virchows Arch A Pathol Anat Hi

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