The use of immunohistochemical method enabled to obtain for the first time the expression of two vasoactive hormones--serotonin and endothelin-1 in human thymus. The high level of the expression of these hormones has been shown in aging. Taking into account the immunoregulatory effects of serotonin and endothelin-1, and especially the activation of T-lymphocyte function under their influence, these data testify to the important role of these hormones in the regulation of immunity in aging.
[Serotonin and endotelin-1 expression in human thymus in aging] Publishing Authors By Initials