Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis.

Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Research Abstract Details 

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Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Abstract Text:

Philipp G Sämann,Jürgen Schlegel,Georg Müller,Franz Prantl,Christoph Emminger,Dorothee P Auer,

We report the case of pathologically proved atypical herpes simplex encephalitis (HSE) in a 40-year-old male patient with AIDS who was followed up by MR imaging, which included diffusion-weighted imaging and proton MR spectroscopy ((1)H-MRS). MR revealed sparing of hippocampi and limbic cortices, necrosis of both cingulate gyri, and cerebellar involvement. Increased diffusivity and severe metabolic alterations were compatible with biopsy findings of necrotizing inflammation. Clinical recovery corresponded with partial metabolite and diffusion normalization and a myo-inositol increase that indicated evolving gliosis formation further corroborated by immunohistochemistry results. (1)H-MRS and diffusion-weighted imaging may both support the diagnosis of HSE in patients with AIDS and help in the follow-up of necrotizing inflammation.

Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Publishing Authors By Initials

PG Sämann,J Schlegel,G Müller,F Prantl,C Emminger,DP Auer,

For similar inorganic chemicals: electrolytes: ions: cations: cations, monovalent: protons research abstracts see: inorganic chemicals: electrolytes: ions: cations: cations, monovalent: protons research

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Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJNR. American journal of neuroradiology

VOLUME: 24

Page Numbers: 2015-9

Journal Abbreviation:

ISSN: 0195-6108

DAY: 14

MONTH: 02

YEAR: 2008

Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Information

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LANGUAGE: eng

NlmUniqueID: 8003708

Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Keywords Mesh Terms:

KEYWORDS: Protons

MESH TERMS: methods

Chemical & Substance for Abstract: Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis. Information

Substance Name: Inositol

Registry Number: 6917-35-7

Grant and Affiliation Information for Serial proton MR spectroscopy and diffusion imaging findings in HIV-related herpes simplex encephalitis.

AFFILIATION: Max-Planck-Institute of Psychiatry, NMR Study Group, Munich, Germany.

Country: United States

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MEDLINETA: AJNR Am J Neuroradiol

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