Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy.

Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy. Research Abstract Details 

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Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy. Abstract Text:

M Hase,K Tsuchihashi,S Yonekura,K Nagao,S Tanaka,K Shimamoto,O Imura,

BACKGROUND: Little is known concerning therapeutic modification of left atrial thrombus in mitral stenosis and its formation after successful balloon valvuloplasty (percutaneous transvenous mitral commissurotomy [PTMC]). OBJECTIVE: To test the roles of the clinical use of anticoagulant therapy and PTMC, serial changes in left atrial thrombus were examined by transesophageal echocardiography in 80 patients with mitral stenosis. RESULTS: No difference in embolic history, New York Heart Association functional class, cardiac rhythm, left atrial size or mitral valve area was found between patients with (n=23) and without (n=57) left atrial thrombus. Diuretic use was the prevalent factor for left atrial thrombi, which were dissolved completely in seven (30.4%) and partially in eight (34.7%) of the patients by adequate warfarin. However, after PTMC (n=53), newly formed thrombus was observed in four of 51 (7.8%) patients, which correlated with left atrial size (at least 50mm), atrial fibrillation and poorly controlled warfarin (thrombo test: 63.8 +/- 18.8% versus 35.9 +/- 17.7%, P<0.005). The newly formed thrombi were dissolved within several weeks. CONCLUSION: Left atrial thrombus in symptomatic mitral stenosis exhibits elusive characteristics and should be strictly monitored even after successful PTMC by transesophageal echocardiography in order to achieve adequate anticoagulation.

Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy. Publishing Authors By Initials

M Hase,K Tsuchihashi,S Yonekura,K Nagao,S Tanaka,K Shimamoto,O Imura,

For similar cardiovascular diseases: vascular diseases: embolism and thrombosis: thrombosis research abstracts see: cardiovascular diseases: vascular diseases: embolism and thrombosis: thrombosis research

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Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy. Journal Published:

PUBLICATION TYPE: Review

Journal: The Canadian journal of cardiology

VOLUME: 12

Page Numbers: 278-84

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ISSN: 1916-7075

DAY: 3

MONTH: Mar

YEAR: 1996

Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy. Information

Number of References: 28

LANGUAGE: eng

NlmUniqueID: 8510280

Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy. Keywords Mesh Terms:

KEYWORDS: Thrombosis

MESH TERMS: ultrasonography

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Grant and Affiliation Information for Serial changes of left atrial thrombus in mitral stenosis: transesophageal echocardiographic studies in candidates for balloon mitral commissurotomy.

AFFILIATION: Second Department of Internal Medicine, Sapporo Medical University, School of Medicine, Japan.

Country: CANADA

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MEDLINETA: Can J Cardiol

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