Selective dorsal rhizotomy: long-term experience from Cape Town.

Selective dorsal rhizotomy: long-term experience from Cape Town. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Selective dorsal rhizotomy: long-term experience from Cape Town. Abstract Text:

Nelleke G Langerak,Robert P Lamberts,A Graham Fieggen,Jonathan C Peter,Warwick J Peacock,Christopher L Vaughan,Nelleke G Langerak,Robert P Lamberts,A Graham Fieggen,Jonathan C Peter,Warwick J Peacock,Christopher L Vaughan,

INTRODUCTION: Given the large number of cerebral palsy patients who have undergone selective dorsal rhizotomy in the past two decades, it is clearly imperative that the clinical community be provided with objective and compelling evidence of the long-term sequelae of the procedure. MATERIALS AND METHODS: In the early 1980s, Peacock in Cape Town shifted the site of the rhizotomy from the conus medullaris to the cauda equina, and in the past 25 years, more than 200 children have been operated on. We have studied the incidence of spinal deformities after multiple-level laminectomy and recorded a 20% incidence of isthmic spondylolysis or grade-I spondylolisthesis. We have also conducted a long-term prospective gait analysis study on a cohort of 14 ambulatory patients who were operated on in 1985. RESULTS: Ten years after surgery, our patients had increased ranges of motion that were within normal limits. Step length was significantly improved, although cadence was unchanged postoperatively and was significantly less than normal age-matched control subjects. DISCUSSION: We have recently tracked down all 14 patients from the original cohort and are currently completing a 20-year prospective follow-up analysis of their neuromuscular function and gait. Our preliminary data suggest that selective dorsal rhizotomy is not only an effective method for alleviating spasticity but it also leads to long-term functional benefits.

Selective dorsal rhizotomy: long-term experience from Cape Town. Publishing Authors By Initials

NG Langerak,RP Lamberts,AG Fieggen,JC Peter,WJ Peacock,CL Vaughan,NG Langerak,RP Lamberts,AG Fieggen,JC Peter,WJ Peacock,CL Vaughan,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Selective dorsal rhizotomy: long-term experience from Cape Town. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Child's nervous system : ChNS : official journal o

VOLUME: 23

Page Numbers: 1003-6

Journal Abbreviation:

ISSN: 0256-7040

DAY: 11

MONTH: 07

YEAR: 2007

Selective dorsal rhizotomy: long-term experience from Cape Town. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8503227

Selective dorsal rhizotomy: long-term experience from Cape Town. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Selective dorsal rhizotomy: long-term experience from Cape Town. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Selective dorsal rhizotomy: long-term experience from Cape Town.

AFFILIATION: MRC/UCT Medical Imaging Research Unit, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, Western Cape, 7925, South Africa.

Country: Germany

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Childs Nerv Syst

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Selective dorsal rhizotomy: long-term experience from Cape Town Related Publications

• ATP-Binding cassette cholesterol transporters and cardiovascular disease.
• Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models.
• Allergic problems in the upper respiratory tract, including the ear.
• Alternative splicing yields novel BMAL2 variants: tissue distribution and functional characterization.
• Anemias of infancy and childhood.
• Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents.
• Bone marrow plasminogen activator inhibitor-1 influences the development of obesity.
• Central adiposity and risk of Barrett's esophagus.
• Dielectric behavior of linear polyelectrolytes.
• Dielectric behavior of polyelectrolytes II. The cylinder.
• Dielectric behavior of polyelectrolytes III. The role of counterion interactions.
• Disclosure of date/acquaintance rape: who reports and when.
• Epidemiology and pathogenesis of esophageal cancer.
• Extending Fitts' Law to manual obstacle avoidance.
• Homonataloin in Aloe species.
• Long-Term Experience With 5-alpha-Reductase Inhibitors.
• Long-Term Experience with 5-alpha-Reductase Inhibitors.
• Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity.
• Markedly impaired fibrinolytic balance contributes to cardiovascular risk in adults with growth hormone deficiency.
• Mutagen sensitivity and neoplastic progression in patients with Barrett's esophagus: a prospective analysis.
• NHS set for pound13m net surplus despite rising levels of debt.
• Plasminogen activator inhibitor-1 has a circadian rhythm in blind individuals.
• Population dynamics of Plasmodium sporogony.
• Reactive site-dependent phenotypic alterations in plasminogen activator inhibitor-1 transgenic mice.
• Regulation of the dopamine transporter by phosphorylation.
• Selective dorsal rhizotomy: long-term experience from Cape Town.
• Sexually mediated shedding of Myxobolus fallax spores during spermiation of Litoria fallax (anura).
• Survival differences by race in nasopharyngeal carcinoma.
• The position of the head and centre of mass during the front foot off-drive in skilled and less-skilled cricket batsmen.
• Transgenic overexpression of plasminogen activator inhibitor-1 promotes the development of polycystic ovarian changes in female mice.