Selective cancer cell killing by alpha-tocopheryl succinate.

Selective cancer cell killing by alpha-tocopheryl succinate. Research Abstract Details 

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Selective cancer cell killing by alpha-tocopheryl succinate. Abstract Text:

J Neuzil,T Weber,N Gellert,C Weber,

We report that alpha-tocopheryl succinate, a vitamin E analogue with pro-apoptotic properties, selectively kills cells with a malignant or transformed phenotype, i.e. multiple haematopoietic and carcinoma cell lines, while being non-toxic to normal, i.e. primary and non-transformed cells. These findings strongly suggest a potential of this micronutrient in the therapy and/or prevention of cancer without significant side-effects.

Selective cancer cell killing by alpha-tocopheryl succinate. Publishing Authors By Initials

J Neuzil,T Weber,N Gellert,C Weber,

For similar heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e research abstracts see: heterocyclic compounds: heterocyclic compounds, 2-ring: benzopyrans: vitamin e research

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Selective cancer cell killing by alpha-tocopheryl succinate. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: British journal of cancer

VOLUME: 84

Page Numbers: 87-9

Journal Abbreviation: Br. J. Cancer

ISSN: 0007-0920

DAY: 5

MONTH: Jan

YEAR: 2001

Selective cancer cell killing by alpha-tocopheryl succinate. Information

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LANGUAGE: eng

NlmUniqueID: 370635

Selective cancer cell killing by alpha-tocopheryl succinate. Keywords Mesh Terms:

KEYWORDS: Vitamin E

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Selective cancer cell killing by alpha-tocopheryl succinate. Information

Substance Name: tocopherol succinate

Registry Number: 17407-37-3

Grant and Affiliation Information for Selective cancer cell killing by alpha-tocopheryl succinate.

AFFILIATION: Institute for Prevention of Cardiovascular Diseases, Ludwig Maximilians University, Pettenkoferstrasse 9, Munich, 80336, Germany.

Country: Scotland

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MEDLINETA: Br J Cancer

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