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Seizures during intracarotid methohexital and amobarbital testing.

Seizures during intracarotid methohexital and amobarbital testing. Research Abstract Details 

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  • Seizures during intracarotid methohexital and amobarbital testing. Abstract Text:

    tobias loddenkemperTobias Loddenkemper,gabriel Gabriel ,stephan u schueleStephan U Schuele,elaine wyllieElaine Wyllie,harold h morrisHarold H Morris,

    BACKGROUND: Methohexital and amobarbital have been used as agents for Wada testing in the presurgical evaluation of patients with epilepsy. Previous experience with methohexital as an anesthetic indicates that methohexital may decrease seizure threshold and may trigger seizures. METHODS: A retrospective chart review of 760 intracarotid amobarbital and methohexital tests was performed to determine the frequency of seizures associated with preoperative intracarotid barbiturate testing for language and memory lateralization. RESULTS: Sixteen patients (2.1%) who had seizures were found. In 3 patients, seizures occurred prior to barbiturate injection, and in 13, following barbiturate injection. After injection of amobarbital, 4 of 538 patients (0.7%) had a seizure. Nine of 222 patients had a seizure after methohexital injection (4.1%) (P=0.001). CONCLUSION: Patients with a previous history of epilepsy may be at higher risk for seizures after methohexital injection as compared with amobarbital injection.

    Seizures during intracarotid methohexital and amobarbital testing. Publishing Authors By Initials

    t loddenkemperT Loddenkemper,g G ,su schueleSU Schuele,e wyllieE Wyllie,hh morrisHH Morris,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

    MEDLINE DATE:

    Seizures during intracarotid methohexital and amobarbital testing. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Epilepsy & behavior : E&B

    VOLUME: 10

    Page Numbers: 49-54

    Journal Abbreviation:

    ISSN: 1525-5050

    DAY: 16

    MONTH: 10

    YEAR: 2006

    Seizures during intracarotid methohexital and amobarbital testing. Information

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    LANGUAGE: eng

    NlmUniqueID: 100892858

    Seizures during intracarotid methohexital and amobarbital testing. Keywords Mesh Terms:

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    Grant and Affiliation Information for Seizures during intracarotid methohexital and amobarbital testing.

    AFFILIATION: Department of Neurology, Cleveland Clinic, Cleveland, OH, USA.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Epilepsy Behav

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