Secretory immunoglobulin A in serum of CF patients.

Secretory immunoglobulin A in serum of CF patients. Research Abstract Details 

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Secretory immunoglobulin A in serum of CF patients. Abstract Text:

J Hein,M Seyfarth,J Brock,H D Kirschnick,S Schober,K Breuel,H U Gülzow,

Increased sIgA values were found in CF patients in about 70 per cent (3 studies with 23, 43, 45 CF patients). With higher severity of CF disease (Shwachman score) we could observe higher sIgA levels. Postmortem histological findings and sIgA concentrations correlated well in 13 cases. Determinations of sIgA in serum could serve as parameter for hepatobiliary involvement in CF. Secretory immunoglobulin A (sIgA) is the predominant immunoglobulin of exocrine secretions. In serum large and frequent elevations of sIgA could be found in patients with chronic liver disease characterized by biliary obstruction (3). Slight and irregular elevations were observed in patients with disorders of gastrointestinal tract and of respiratory tract as well as in lactating women (3). Manifestations of the hepatobiliary system in CF will become more important with advancing age and progressively higher life expectancy of CF patients. A simple reliable test for detection of hepatobiliary involvement in CF would be useful.

Secretory immunoglobulin A in serum of CF patients. Publishing Authors By Initials

J Hein,M Seyfarth,J Brock,HD Kirschnick,S Schober,K Breuel,HU Gülzow,

For similar digestive system diseases: liver diseases research abstracts see: digestive system diseases: liver diseases research

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Secretory immunoglobulin A in serum of CF patients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta Universitatis Carolinae. Medica

VOLUME: 36

Page Numbers: 169-70

Journal Abbreviation:

ISSN: 0001-7116

DAY: 20

MONTH: 02

YEAR: 1990

Secretory immunoglobulin A in serum of CF patients. Information

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LANGUAGE: eng

NlmUniqueID: 2985169

Secretory immunoglobulin A in serum of CF patients. Keywords Mesh Terms:

KEYWORDS: Liver Diseases

MESH TERMS: immunology

Chemical & Substance for Abstract: Secretory immunoglobulin A in serum of CF patients. Information

Substance Name: Immunoglobulin A, Secretory

Registry Number: 0

Grant and Affiliation Information for Secretory immunoglobulin A in serum of CF patients.

AFFILIATION: Department of Pediatrics, Wilhelm-Pieck-University Rostock, German Democratic Republic.

Country: CZECHOSLOVAKIA

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MEDLINETA: Acta Univ Carol [Med] (Praha)

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