Secretion of inorganic phosphate in the rat nephron.

Secretion of inorganic phosphate in the rat nephron. Research Abstract Details 

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Secretion of inorganic phosphate in the rat nephron. Abstract Text:

J F Boundry,U Troehler,M Touabi,H Fleisch,J P Bonjour,

1.The existence of tubular secretion of inorganic phosphate (Pi) in the mammalian kidney has been investigated by studying the renal response of rats infused with sodium phosphate by three different techniques. 2. Clearance studies indicate that, in anaesthetized rats, the net tubular reabsorption decreases markedly in response to Pi infusion. In conscious rats, the clearance of Pi slightly exceeded that of inulin at high plasma Pi concentration. 3. Free-flow micropuncture in control rats showed a net tubular reabsorption of Pi along the proximal tubule, and probably between the end of the distal tubule and the ureteral urine. In phosphate-loaded rats, whether receiving parathyroid hormone or not, an apparent net secretion of Pi was observed between the end of the distal tubule and the reteral urine. In the phosphate-loaded group receiving parthyroid hormone, net secretion was also observed very early in the proximal tubule followed by a predominant reabsorption along this segment. Thus the early proximal tubule and probably also the terminal nephron can be the site of either net reabsorption or net secretion. 4. Microperfusions of proximal tubules show a fall in the specific radioactivity of the perfused radioactive Pi solution, indicating entry of Pi into the lumen.

Secretion of inorganic phosphate in the rat nephron. Publishing Authors By Initials

JF Boundry,U Troehler,M Touabi,H Fleisch,JP Bonjour,

For similar surgical procedures, operative: endocrine surgical procedures: thyroidectomy research abstracts see: surgical procedures, operative: endocrine surgical procedures: thyroidectomy research

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Secretion of inorganic phosphate in the rat nephron. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Clinical science and molecular medicine. Supplemen

VOLUME: 48

Page Numbers: 475-89

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ISSN: 0144-4107

DAY: 12

MONTH: Jun

YEAR: 1975

Secretion of inorganic phosphate in the rat nephron. Information

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LANGUAGE: eng

NlmUniqueID: 7907311

Secretion of inorganic phosphate in the rat nephron. Keywords Mesh Terms:

KEYWORDS: Thyroidectomy

MESH TERMS: physiology

Chemical & Substance for Abstract: Secretion of inorganic phosphate in the rat nephron. Information

Substance Name: Calcium

Registry Number: 7440-70-2

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Country: ENGLAND

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MEDLINETA: Clin Sci Mol Med Suppl

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