Secretin-stimulating MRCP in patients with pancreatobiliary maljunction and occult pancreatobiliary reflux: direct demonstration of pancreatobiliary reflux.

Secretin-stimulating MRCP in patients with pancreatobiliary maljunction and occult pancreatobiliary reflux: direct demonstration of pancreatobiliary reflux. Research Abstract Details 

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Secretin-stimulating MRCP in patients with pancreatobiliary maljunction and occult pancreatobiliary reflux: direct demonstration of pancreatobiliary reflux. Abstract Text:

Utaroh Motosugi,Tomoaki Ichikawa,Tsutomu Araki,Fumiaki Kitahara,Tadashi Sato,Jun Itakura,Hideki Fujii,Utaroh Motosugi,Tomoaki Ichikawa,Tsutomu Araki,Fumiaki Kitahara,Tadashi Sato,Jun Itakura,Hideki Fujii,

We propose the hypothesis that the enlargement of the common bile duct (CBD) or gallbladder (GB) that is occasionally demonstrated on magnetic resonance cholangiopancreatography (MRCP) after secretin stimulation is caused by pancreatobiliary reflux. Recently, occult pancreatobiliary reflux (OPR) has been demonstrated in patients without morphological pancreatobiliary maljunction (MPBM). The aim of this study was to evaluate the efficacy of secretin-stimulating MRCP (SMRCP) in the diagnosis of pancreatobiliary reflux. The study included 14 patients with MPBM and 32 patients with a normal pancreatobiliary junction. OPR was evaluated by bile collection and diagnosed in seven of the 32 patients. All the patients underwent SMRCP; the related findings were considered positive when enlargement of the CBD or GB was observed. Positive findings on SMRCP were observed in all MPBM patients. In the patients with normal pancreatobiliary junction, there was significant difference between the mean amylase levels in the patients with positive and negative SMRCP findings (mean, 4,755.7 and 29.7 IU/l). The sensitivity and specificity of SMRCP for diagnosing OPR was 85.7% and 68.0%, respectively. SMRCP provides a non invasive method for excluding PBR and can identify patients who could benefit from bile duct sampling to diagnose OPR.

Secretin-stimulating MRCP in patients with pancreatobiliary maljunction and occult pancreatobiliary reflux: direct demonstration of pancreatobiliary reflux. Publishing Authors By Initials

U Motosugi,T Ichikawa,T Araki,F Kitahara,T Sato,J Itakura,H Fujii,U Motosugi,T Ichikawa,T Araki,F Kitahara,T Sato,J Itakura,H Fujii,

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Secretin-stimulating MRCP in patients with pancreatobiliary maljunction and occult pancreatobiliary reflux: direct demonstration of pancreatobiliary reflux. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European radiology

VOLUME: 17

Page Numbers: 2262-7

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ISSN: 0938-7994

DAY: 20

MONTH: 04

YEAR: 2007

Secretin-stimulating MRCP in patients with pancreatobiliary maljunction and occult pancreatobiliary reflux: direct demonstration of pancreatobiliary reflux. Information

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LANGUAGE: eng

NlmUniqueID: 9114774

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AFFILIATION: Department of Radiology, University of Yamanashi, 1110 Shimokato, Chuo-shi, Yamanashi, 409-3898, Japan. utaroh-motosugi@nifty.com

Country: Germany

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MEDLINETA: Eur Radiol

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