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Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma.

Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma. Research Abstract Details 

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  • Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma. Abstract Text:

    kazumichi yamadaKazumichi Yamada,hideo takeshimaHideo Takeshima,tomotaka sakuramaTomotaka Sakurama,jun-ichi kuratsuJun-Ichi Kuratsu,kazumichi yamadaKazumichi Yamada,hideo takeshimaHideo Takeshima,tomotaka sakuramaTomotaka Sakurama,jun-ichi kuratsuJun-Ichi Kuratsu,kazumichi yamadaKazumichi Yamada,hideo takeshimaHideo Takeshima,tomotaka sakuramaTomotaka Sakurama,jun-ichi kuratsuJun-Ichi Kuratsu,

    BACKGROUND: Cervical dystonia associated with structural lesion is uncommon. We report the first patient with secondary CD after stereotactic radiosurgery for thalamic glioma. Possible network abnormalities relevant to manifestation of CD were discussed. CASE DESCRIPTION: A 27-year-old woman complaining of headache and left motor weakness was found to have a thalamic tumor on the right side. The lesion was totally removed using transventricular approach. Histopathologically, tumor samples manifested features of anaplastic astrocytoma. She underwent stereotactic radiosurgery in addition to the conventional radiation and chemotherapy. Afterward, she returned to her usual life without any neurological deficits. Sixteen months postoperatively, the patient developed forced head tilting to the left side combined with chin lift. On the TWSTRS, she registered 15 for torticollis severity. The abnormal head posturing was alleviated by the sensory trick of touching her face with her right hand. Irregular-shaped lesion involving the thalamus, lenticular nuclei, midbrain, pons, and cerebellum was presented on magnetic resonance images. Steroid therapy effectively diminished the lesion size, and her abnormal head posturing was gradually ameliorated (TWSTRS severity scale = 3). CONCLUSION: The clinical-neuroradiological course of the present case strongly suggested that the lesion detected long after the surgery was due to radiation necrosis. The present study may provide a critical information in understanding pathophysiological mechanisms of CD that may involve substantial interactions between olivocerebellar and basal ganglia-thalamocortical circuits.

    Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma. Publishing Authors By Initials

    k yamadaK Yamada,h takeshimaH Takeshima,t sakuramaT Sakurama,j kuratsuJ Kuratsu,k yamadaK Yamada,h takeshimaH Takeshima,t sakuramaT Sakurama,j kuratsuJ Kuratsu,k yamadaK Yamada,h takeshimaH Takeshima,t sakuramaT Sakurama,j kuratsuJ Kuratsu,

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    Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Surgical neurology

    VOLUME: 68

    Page Numbers: 665-70

    Journal Abbreviation:

    ISSN: 0090-3019

    DAY: 6

    MONTH: Dec

    YEAR: 2007

    Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma. Information

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    LANGUAGE: eng

    NlmUniqueID: 367070

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    Grant and Affiliation Information for Secondary cervical dystonia following stereotactic radiosurgery in a patient with thalamic glioma.

    AFFILIATION: Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan. yamadakazu@fc.kuh.kumamoto-u.ac.jp

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Surg Neurol

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