Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review.

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Abstract Text:

James P Malone,Roger J Levin,

The purpose of this study was to identify the histopathology, location, and latency interval for the development of second malignant tumors (SMT) after successful treatment for nasopharyngeal carcinoma (NPC). Of 55 patients, four developed SMT after successful treatment of NPC in a single institutional series for an incidence of 7%. An additional 31 patients with SMT after treatment for NPC were identified from the literature. At minimum, all patients were treated with radiotherapy to the primary site. The histopathology of SMT included sarcoma (69%), squamous cell carcinoma (17%), adenocarcinoma (6%), meningioma (6%), and lymphoma (3%). SMT occurred at various sites in the head and neck, but most (51%) arose in the sinonasal cavity. For the entire group, the mean latency interval between treatment for NPC and the development of SMT was 11.8 years. These findings indicate that the development of SMT in patients achieving long-term survival after treatment for NPC may be radiation induced. Long-term follow-up for these patients is important to assess for this potentially late complication.

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Publishing Authors By Initials

JP Malone,RJ Levin,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Skull base : official journal of North American Sk

VOLUME: 12

Page Numbers: 87-91

Journal Abbreviation:

ISSN: 1531-5010

DAY: 14

MONTH: May

YEAR: 2002

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101090660

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review.

AFFILIATION:

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Skull Base

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review Related Publications

• A second-site suppressor significantly improves the defective phenotype imposed by mutation of an aromatic residue in the N-terminal domain of the HIV-1 capsid protein.
• Altered brain activation during cognitive control in patients with moderate to severe traumatic brain injury.
• Altered hypothalamic leptin, insulin, and melanocortin binding associated with moderate-fat diet and predisposition to obesity.
• Apoptosis is required during early stages of tail regeneration in Xenopus laevis.
• Assessment of cognitive functioning of methadone-maintenance patients: impact of adult ADHD and current cocaine dependence.
• Comment on "Direct measurement of the 'Giant' adiabatic temperature change in Gd5Si2Ge2".
• Decision-making after traumatic brain injury in children: a preliminary study.
• Diffusion tensor imaging in the corpus callosum in children after moderate to severe traumatic brain injury.
• Effect of age on the response to in vitro ischemia and reperfusion of the rabbit bladder.
• Effect of bilateral in vivo ischemia/reperfusion on the activities of superoxide dismutase and catalase: response to a standardized grape suspension.
• Effect of short-term outlet obstruction on rat bladder nerve density and contractility.
• Evidence for the regulation of left-right asymmetry in Ciona intestinalis by ion flux.
• H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration.
• Hippocampus, amygdala, and basal ganglia morphometrics in children after moderate-to-severe traumatic brain injury.
• Inverse drug screens: a rapid and inexpensive method for implicating molecular targets.
• Is the early left-right axis like a plant, a kidney, or a neuron? The integration of physiological signals in embryonic asymmetry.
• Management of the acute asthmatic attack in childhood.
• Moderators' Summary: Wound Management (Session II).
• New developments in flap techniques.
• One-year follow-up study of suicide attempters treated for drug dependence.
• Periodontal diseases--a modifiable source of systemic inflammation for the end-stage renal disease patient on haemodialysis therapy?
• Predictors of cannabis dependence recovery among epidemiological survey respondents in the United States.
• Second malignant tumors after treatment of nasopharyngeal carcinoma: four case reports and literature review.
• Synthesis and characterization of a novel class of reducing agents that are highly neuroprotective for retinal ganglion cells.
• Technology-based training in cognitive behavioral therapy for substance abuse counselors.
• The effects of cyclical oestrogen on bladder and urethral structure and function.
• Treating depression in substance abusers.
• Vascularized fibula graft for the traumatically induced long-bone defect.
• Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats.
• Working memory brain activation following severe traumatic brain injury.