Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography.

Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Research Abstract Details 

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Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Abstract Text:

Single photon emission tomography with split-dose technetium-99m-d, l-hexamethyl-propylene amine oxime was used to measure regional cerebral blood flow (rCBF) during a memory-activation paradigm in a group of 18 medicated DSM-III-R schizophrenic patients. The relationship between clinical features of schizophrenia and rCBF patterns was examined. Increased blood flow to the left basal ganglia was revealed during activation in patients reporting hallucinations in the previous month, a finding that was not influenced by medication dose or other confounding variables. This result adds to previous functional imaging studies that have related basal ganglia abnormalities to hallucinatory phenomena and suggests that left basal ganglia hyperactivity may be relevant to an internal monitoring deficit responsible for the appearance of those symptoms in schizophrenia.

Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Publishing Authors By Initials

For similar psychological phenomena and processes: mental processes: learning: verbal learning research abstracts see: psychological phenomena and processes: mental processes: learning: verbal learning research

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Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Psychiatry research

VOLUME: 61

Page Numbers: 255-64

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 10

MONTH: Nov

YEAR: 1995

Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Keywords Mesh Terms:

KEYWORDS: Verbal Learning

MESH TERMS: physiology

Chemical & Substance for Abstract: Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Information

Substance Name: Technetium Tc 99m Exametazime

Registry Number: 100504-35-6

Grant and Affiliation Information for Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography.

AFFILIATION: Department of Psychological Medicine, Institute of Psychiatry, London, UK.

Country: IRELAND

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MEDLINETA: Psychiatry Res

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