Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants.

Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Research Abstract Details 

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Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Abstract Text:

Salivary SIgA antibodies against RS virus were studied in 105 children during the first year of life. The infants were divided into groups according to their risk of atopy. At birth 13 neonates showed measurable amounts of SIgA to RS virus. In another 26 children specific antibodies were detected but in concentrations too low for quantitative analysis. During the first year of life this increased to 29 antibody-positive samples with measurable amounts of antibody and 39 with concentrations too low for quantitative determination. At this time 8 children of the high risk group had developed symptoms of allergy. None of these children had measurable amounts of SIgA anti-RSV in their saliva. In comparison, 10 of the remaining 26 high risk infants without symptoms of allergy did have such antibodies. Atopic infants had significantly more respiratory infections during the first year of life than nonatopic infants. The avidity of SIgA anti-RSV in neonatal samples was significantly higher than avidity determined in breast milk SIgA but comparable to the avidity of serum IgG. During the first year of life a continuing decrease of salivary SIgA avidity was observed.

Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Publishing Authors By Initials

For similar fluids and secretions: bodily secretions: saliva research abstracts see: fluids and secretions: bodily secretions: saliva research

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Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pediatric allergy and immunology : official public

VOLUME: 5

Page Numbers: 46-52

Journal Abbreviation: Pediatr Allergy Immunol

ISSN: 0905-6157

DAY: 28

MONTH: Feb

YEAR: 1994

Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Information

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LANGUAGE: eng

NlmUniqueID: 9106718

Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Keywords Mesh Terms:

KEYWORDS: Saliva

MESH TERMS: immunology

Chemical & Substance for Abstract: Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants. Information

Substance Name: Immunoglobulin E

Registry Number: 37341-29-0

Grant and Affiliation Information for Salivary anti-RSV IgA antibodies and respiratory infections during the first year of life in atopic and non-atopic infants.

AFFILIATION: Children's Hospital, Philipps University, Marburg, Germany.

Country: DENMARK

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MEDLINETA: Pediatr Allergy Immunol

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