Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review.

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Abstract Text:

BACKGROUND: Fecal incontinence and constipation are disabling conditions that reduce quality of life. If conservative treatment fails, one option is sacral nerve stimulation (SNS), a minimally invasive technique allowing modulation of the nerves and muscles of the pelvic floor and hindgut. OBJECTIVES: To assess the effects of SNS for fecal incontinence and constipation in adults. SEARCH STRATEGY: We searched the Cochrane Incontinence Group Specialized Trials Register (searched 24 April 2007) and the reference lists of relevant articles. SELECTION CRITERIA: All randomized or quasi-randomized trials assessing the effects of SNS for fecal incontinence or constipation in adults. DATA COLLECTION AND ANALYSIS: Two review authors independently screened the search results, assessed the methodological quality of the included studies, and undertook data extraction. MAIN RESULTS: Three crossover studies were included. Two, enrolling 34 (Leroi) and two participants (Vaizey), assessed the effects of SNS for fecal incontinence, and one (Kenefick), enrolling two participants, assessed SNS for constipation.In the study by Leroi, following the crossover period, participants, while still blinded, chose the period of stimulation they had preferred. Outcomes at different time points were reported separately for 19 participants who preferred the "on" and five who preferred the "off" period. For the group of 19, the median (range) episodes of fecal incontinence per week fell from 1.7 (0-9) during the "off" period to 0.7 (0-5) during the "on" period; for the group of five, however, the median (range) rose from 1.7 (0-11) during the "off" period compared with 3.7 (0-11) during the "on" period. Vaizey reported an average of six, and one, episodes of fecal incontinence per week during the "off" and "on" periods, respectively. Leroi reported that four of 27 participants experienced an adverse event resulting in removal of the stimulator; Vaizey did not report adverse events.For SNS for constipation, during the "off" crossover period the participants experienced an average of two bowel movements per week, compared with five during the "on" period. Abdominal pain and bloating occurred 79% of the time during the "off" period compared with 33% during the "on" period. No adverse events occurred. AUTHORS' CONCLUSIONS: The very limited evidence from the included studies suggests that SNS can improve continence in selected people with fecal incontinence, and reduce symptoms in selected people with constipation. However, temporary, percutaneous stimulation for a 2-3-week period does not always successfully identify those for whom a permanent implant will be beneficial. Larger, good quality randomized crossover trials are needed to allow the effects of SNS for these conditions to be assessed with more certainty.

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Neurourology and urodynamics

VOLUME: 27

Page Numbers: 155-61

Journal Abbreviation: Neurourol. Urodyn.

ISSN: 0733-2467

DAY: 17

MONTH: 03

YEAR: 2008

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8303326

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review.

AFFILIATION:

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Neurourol Urodyn

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review Related Publications

• Assessing the preventive effects of cognitive therapy following relief of depression: A methodological innovation.
• Biochemistry: radicals by reduction.
• Environmental effects on mastitis and milk quality.
• Evaluation of a thyroid panel; practical application of scintillation counter in diagnosis of diseases of the thyroid.
• Evidence from Mössbauer spectroscopy for distinct [2Fe-2S](2+) and [4Fe-4S](2+) cluster binding sites in biotin synthase from Escherichia coli.
• Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy.
• Intensified silicon photodiode array detector linearity: application to coherent anti-Stokes Raman spectroscopy.
• Irritable bowel syndrome: Does gender matter?
• Laminin-Induced Activation of Rac1 and JNKp46 Is Initiated by Src Family Kinases and Mimics the Effects of Skeletal Muscle Contraction.
• Lessons of epidemiology of diabetes.
• Loss of iron-sulfur clusters from biotin synthase as a result of catalysis promotes unfolding and degradation.
• Magnetic Susceptibility Artifacts on MRI: A Hairy Situation.
• Malignant melanoma; report of a case.
• Management of solid tumors in children: contribution of computed tomography.
• Mastitis in dairy cows.
• Mechanical milking and its relationship to mastitis.
• Metastatic primitive neuroectodermal tumor to the kidney.
• Nighttime plasma cortisol secretion and EEG sleep--are they associated?
• Nutritional status and wound severity of overweight and obese patients with venous leg ulcers: A pilot study.
• Ocular and testicular abnormalities in alopecia areata.
• Oncologic outcomes of extravesical stapling of distal ureter in laparoscopic nephroureterectomy.
• Pharmacy students learn in outpatient service.
• Plasma cholinesterase isozymes and REM latency in schizophrenia.
• Proteins and insulin release.
• Reducing relapse and recurrence in unipolar depression: a comparative meta-analysis of cognitive-behavioral therapy's effects.
• Role of the [2Fe-2S]2+ cluster in biotin synthase: mutagenesis of the atypical metal ligand arginine 260.
• Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review.
• Time to label sodium in drug treatments?
• Total laparoscopic gastrocystoplasty: experimental technique in a porcine model.
• What is the prognostic value of the pT3a tumor classification for renal cell carcinoma?