Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease.

Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. Research Abstract Details 

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Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. Abstract Text:

Claudine M Baldwin,Gillian M Keating,Claudine M Baldwin,Gillian M Keating,

A transdermal patch formulation of the non-ergolinic dopamine agonist rotigotine (Neupro((R))) is indicated for use as monotherapy in the treatment of early-stage Parkinson's disease or, in the EU, as an adjunct to levodopa across all disease stages. Transdermal rotigotine is an effective and generally well tolerated addition to the armamentarium for the control of Parkinson's disease, with the once-daily transdermal patch system offering several practical advantages and the possible benefits of avoiding pulsatile dopaminergic stimulation. Transdermal rotigotine was superior to placebo in patients with early-stage and advanced Parkinson's disease, although noninferiority to the oral dopamine agonists ropinirole or pramipexole was not consistently demonstrated. Additional active comparator trials would be of interest. In the meantime, transdermal rotigotine offers a convenient new treatment option for patients with Parkinson's disease.

Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. Publishing Authors By Initials

CM Baldwin,GM Keating,CM Baldwin,GM Keating,

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Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: CNS drugs

VOLUME: 21

Page Numbers: 1039-55

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ISSN: 1172-7047

DAY: 20

MONTH: 11

YEAR: 2007

Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. Information

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LANGUAGE: eng

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AFFILIATION: Wolters Kluwer Health | Adis, Auckland, New Zealand, an editorial office of Wolters Kluwer Health, Conshohocken, Pennsylvania, USA.

Country: New Zealand

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MEDLINETA: CNS Drugs

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