Role of radiologic features in the management of papillary lesions of the breast.

Role of radiologic features in the management of papillary lesions of the breast. Research Abstract Details 

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Role of radiologic features in the management of papillary lesions of the breast. Abstract Text:

W W M Lam,W C W Chu,A P Y Tang,G Tse,T K F Ma,

OBJECTIVE: The purpose of our study was to assess the role of imaging and core biopsy in the management of patients with papillary lesions of the breast. MATERIALS AND METHODS: Clinical records and mammographic and sonographic findings of 40 women with papillary lesions in the breast were retrieved. The imaging features and cytologic findings were correlated with histologic findings. RESULTS: Fifty-six papillary lesions in 40 patients underwent either mastectomy, segmental duct resection, or excision biopsy. There were three papillary carcinomas, 13 papillaryal lesions with carcinoma in situ, one atypical papilloma, four sclerosed papillomata, and 35 papillomata. Of these lesions, 37.5% (21/56) and 82.1% (46/56) could be detected on mammography and sonography, respectively. Galactography and dilated ducts helped to suggest the papillary nature of the lesions. However, mammography and sonography were not able to predict malignancy (sensitivity, 69% and 56%, respectively; specificity, 25% and 90%; positive predictive value [PPV], 60% and 75%; and negative predictive value [NPV], 33% and 90%). Combined interpretation of mammography and sonography gave a sensitivity of 61%, specificity of 33%, PPV of 85%, and NPV of 13%. Fine-needle aspiration gave a sensitivity of 44%, specificity of 68%, PPV of 31%, and NPV of 79%, whereas core biopsy gave a sensitivity of 82%, specificity of 100%, PPV of 100%, and NPV of 83% in the diagnosis of malignancy. CONCLUSION: Radiologic features are not sufficiently sensitive or specific to differentiate benign from malignant papillary lesions. Fine-needle aspiration and core biopsy have pitfalls, and the need for surgical excision of all papillary lesions should be revisited.

Role of radiologic features in the management of papillary lesions of the breast. Publishing Authors By Initials

WW Lam,WC Chu,AP Tang,G Tse,TK Ma,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, mammary research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: ultrasonography: ultrasonography, mammary research

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Role of radiologic features in the management of papillary lesions of the breast. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 186

Page Numbers: 1322-7

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ISSN: 1546-3141

DAY: 15

MONTH: May

YEAR: 2006

Role of radiologic features in the management of papillary lesions of the breast. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Role of radiologic features in the management of papillary lesions of the breast. Keywords Mesh Terms:

KEYWORDS: Ultrasonography, Mammary

MESH TERMS: surgery

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Grant and Affiliation Information for Role of radiologic features in the management of papillary lesions of the breast.

AFFILIATION: Department of Diagnostic Radiology and Organ Imaging, Rm. 27029, Prince of Wales Hospital, Ngan Shing St., Shatin, Hong Kong. wynnie@cuhk.edu.hk <wynnie@cuhk.edu.hk>

Country: United States

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MEDLINETA: AJR Am J Roentgenol

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