Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers?

Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Research Abstract Details 

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Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Abstract Text:

Maureen N Ajuebor,Maureen N Ajuebor,

Information regarding the functional role of the innate immune T cell, invariant natural killer T (iNKT) cells, in the pathophysiology of liver diseases continues to emerge. Results from animal studies suggest that iNKT cells can have divergent roles by specifically promoting the development of proinflammatory or anti-inflammatory responses in liver diseases. In this themes article, I discuss the critical evidence from animal models that demonstrate a vital role for iNKT cells in the pathophysiology of liver diseases with emphasis on viral, autoimmune, and toxin-induced liver diseases. Furthermore, I discuss the controversial issues (including iNKT cell apoptosis) that typify some of these studies. Finally, I highlight areas that require additional investigation.

Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Publishing Authors By Initials

MN Ajuebor,MN Ajuebor,

For similar digestive system diseases: liver diseases research abstracts see: digestive system diseases: liver diseases research

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Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Journal Published:

PUBLICATION TYPE: Review

Journal: American journal of physiology. Gastrointestinal a

VOLUME: 293

Page Numbers: G651-6

Journal Abbreviation: Am. J. Physiol. Gastrointest.

ISSN: 0193-1857

DAY: 12

MONTH: 07

YEAR: 2007

Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Information

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LANGUAGE: eng

NlmUniqueID: 100901227

Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Keywords Mesh Terms:

KEYWORDS: Liver Diseases

MESH TERMS: immunology

Chemical & Substance for Abstract: Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers? Information

Substance Name: alpha-galactosylceramide

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Grant and Affiliation Information for Role of NKT cells in the digestive system. I. Invariant NKT cells and liver diseases: is there strength in numbers?

AFFILIATION: Dept. of Molecular & Cellular Physiology, Louisiana State Univ. Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130-3932, USA. majueb@lsuhsc.edu

Country: United States

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MEDLINETA: Am J Physiol Gastrointest Live

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