Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats.

Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Research Abstract Details 

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Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Abstract Text:

S Ueda,T Yoshikawa,S Takahashi,H Ichikawa,M Yasuda,H Oyamada,T Tanigawa,S Sugino,M Kondo,

Ischemia and reperfusion are of the greatest importance in the pathology of many diseases. We investigated the roles of oxygen-derived free radicals and lipid peroxidation in gastric mucosal injury, such as spotty and linear hemorrhagic erosions, induced in rats by ischemia-reperfusion. The gastric mucosal injury and the increase in thiobarbituric acid (TBA) reactants in the gastric mucosa induced by ischemia-reperfusion were significantly inhibited by treatment with SOD and catalase. These results suggest that oxygen-derived free radicals and lipid peroxidation play important roles in the pathogenesis of acute gastric mucosal lesions induced by ischemia-reperfusion.

Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Publishing Authors By Initials

S Ueda,T Yoshikawa,S Takahashi,H Ichikawa,M Yasuda,H Oyamada,T Tanigawa,S Sugino,M Kondo,

For similar heterocyclic compounds: heterocyclic compounds, 1-ring: pyrimidines: pyrimidinones: barbiturates: thiobarbiturates research abstracts see: heterocyclic compounds: heterocyclic compounds, 1-ring: pyrimidines: pyrimidinones: barbiturates: thiobarbiturates research

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Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Scandinavian journal of gastroenterology. Suppleme

VOLUME: 162

Page Numbers: 55-8

Journal Abbreviation: Scand. J. Gastroenterol. Suppl

ISSN: 0085-5928

DAY: 13

MONTH: 02

YEAR: 1989

Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Information

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LANGUAGE: eng

NlmUniqueID: 437034

Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Keywords Mesh Terms:

KEYWORDS: Thiobarbiturates

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Information

Substance Name: Superoxide Dismutase

Registry Number: EC 1.15.1.1

Grant and Affiliation Information for Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats.

AFFILIATION: First Department of Medicine, Kyoto Prefectural University of Medicine, Japan.

Country: NORWAY

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MEDLINETA: Scand J Gastroenterol Suppl

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