Role of cysteine cathepsins in matrix degradation and cell signalling.

Role of cysteine cathepsins in matrix degradation and cell signalling. Research Abstract Details 

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Role of cysteine cathepsins in matrix degradation and cell signalling. Abstract Text:

Cysteine cathepsins participate in extracellular matrix (ECM) degradation and remodelling and thus influence important cellular processes such as cell transformation and differentiation, motility, adhesion, invasion, angiogenesis, and metastasis. Also, cathepsins are involved in cell signalling and are capable of activating specific cell receptors and growth factors or liberating them from the ECM. In this review we emphasize recent studies on cathepsins in regard to ECM degradation and cell signalling.

Role of cysteine cathepsins in matrix degradation and cell signalling. Publishing Authors By Initials

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Role of cysteine cathepsins in matrix degradation and cell signalling. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Connective tissue research

VOLUME: 49

Page Numbers: 193-6

Journal Abbreviation: Connect. Tissue Res.

ISSN: 1607-8438

DAY: 28

MONTH: 07

YEAR: 2008

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LANGUAGE: eng

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Grant and Affiliation Information for Role of cysteine cathepsins in matrix degradation and cell signalling.

AFFILIATION: Department of Pharmaceutical Biology, University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia. natasa.obermajer@ffa.uni-lj.si

Country: United States

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MEDLINETA: Connect Tissue Res

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