Role and clinical importance of Helicobacter pylori infection in hemodialysis patients.

Role and clinical importance of Helicobacter pylori infection in hemodialysis patients. Research Abstract Details 

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Role and clinical importance of Helicobacter pylori infection in hemodialysis patients. Abstract Text:

F P ,B Cudia,Gi Romano,G Cocchiara,V Li Vecchi,M A ,C ,L Lo Coco,M Li Vecchi,M Romano,

English version Dyspepsia is an extrarenal symptom frequently found in hemodialysed patients; it is due to chronic renal failure, and uremic gastritis is a specific associated condition in chronic renal failure (CRF). On the other hand, in the general population, Helicobacter pylori infection is an important dyspepsia-related risk factor; its close connections with gastro-duodenal pathology are already known, above all the peptic disease in a really exclusive way. By observation of a dyalitic group of patients, opportunely matched with a no CRF group, we evaluated CRF-associated uremia and Helicobacter pylori infection which could eventually interact causing symptoms and lesions. A statistical analysis of obtained data allowed us to conclude that, although there is not, from an epidemiological view-point, a larger diffusion of Helicobacter pylori among dyalitic patients compared to general population, moreover the infection is uremia-synergic in causing gastro-duodenal symptoms and lesions. These findings, therefore, suggest systematically investigation a possible Helicobacter pylori infection in CRF patients and its relation to gastritis grading, and searching for probable active peptic lesions. Versione italiana La dispepsia è un sintomo estrarenale che si osserva frequentemente nei pazienti dializzati a causa dell'insufficienza renale cronica (CRF) e della gastrite uremica. Nella popolazione a generale l'Helicobacter Pylori (HP) è un fattore di rischio per la malattia peptica, le gastriti croniche e la corrispettiva sintomatologia dispeptica. Nel presente studio vengono osservati un gruppo di pazienti dializzati e confrontati con un gruppo di pazienti con funzione renale normale e con uno con CRF. Viene valutata l'associazione tra l'uremia e l'infezione da HP e l'eventuale correlazione con la sintomatologia dispeptica e le lesioni anatomo patologiche del tratto gastroenterico superiore. L'analisi statistica ci ha permesso di concludere che dal punto di vista epidemiologico non c'è ampia diffusione dell'infezioni da HP nei pazienti dializzati rispetto alla popolazione normale. Si evince, comunque che l'infezione da HP può essere la causa di lesioni anatomo patologiche del tratto digestivo superiore e della sintomatologia ad essa correlata.

Role and clinical importance of Helicobacter pylori infection in hemodialysis patients. Publishing Authors By Initials

FP ,B Cudia,G Romano,G Cocchiara,V Li Vecchi,MA ,C ,L Lo Coco,M Li Vecchi,M Romano,

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Role and clinical importance of Helicobacter pylori infection in hemodialysis patients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Il Giornale di chirurgia

VOLUME: 29

Page Numbers: 81-4

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ISSN: 0391-9005

DAY: 27

MONTH: Mar

YEAR: 2008

Role and clinical importance of Helicobacter pylori infection in hemodialysis patients. Information

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LANGUAGE: eng

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Country: Italy

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MEDLINETA: G Chir

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