Risk of a new benzodiazepine prescription in relation to recent hospitalization.

Risk of a new benzodiazepine prescription in relation to recent hospitalization. Research Abstract Details 

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Risk of a new benzodiazepine prescription in relation to recent hospitalization. Abstract Text:

OBJECTIVE: To determine if recent hospital admission was associated with new outpatient prescribing of benzodiazepines among community-dwelling older people. DESIGN: Nested case-control study using administrative data sets of the provincial health insurance board. SETTING: Province of Quebec. PARTICIPANTS: Cases were 4127 community-dwelling older people who were newly dispensed a benzodiazepine during an 8-month period in 1990. Controls were 16,486 community-dwelling older people who were dispensed any drug (except a benzodiazepine) on the same day as the case-defining index prescription. EXPOSURE AND OUTCOME MEASURES: Admission to an acute care hospital within a 30-day period before a new dispensing of a benzodiazepine. Other variables measured were patient age, gender, number of ambulatory physician visits, healthcare region, Chronic Disease Score (CDS), and use of drugs for depression and psychosis. RESULTS: Cases were more than three times as likely as controls to have been hospitalized in the 30-day period before the index date (adjusted odds ratio (OR) 3.09; 95% CI, 2.78-3.45). The use of prescription drugs for physical health problems modified this association in that cases who used more medication were also more likely to receive a new benzodiazepine prescription following a recent hospital admission (adjusted OR 4.09; 95% CI, 3.59-4.65 when the CDS was equal to 5 vs adjusted OR 1.96; 95% CI, 1.66-2.31 when the CDS was equal to 0). CONCLUSIONS: Recent hospitalization confers an increased risk of a new outpatient benzodiazepine prescription among community-dwelling older people in Quebec. Those who use more medication, and who may be more vulnerable to drug-related adverse events, are more likely to be newly dispensed a benzodiazepine following a recent, acute-care hospital admission.

Risk of a new benzodiazepine prescription in relation to recent hospitalization. Publishing Authors By Initials

For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk research

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Risk of a new benzodiazepine prescription in relation to recent hospitalization. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of the American Geriatrics Society

VOLUME: 47

Page Numbers: 184-8

Journal Abbreviation: J Am Geriatr Soc

ISSN: 0002-8614

DAY: 10

MONTH: Feb

YEAR: 1999

Risk of a new benzodiazepine prescription in relation to recent hospitalization. Information

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LANGUAGE: eng

NlmUniqueID: 7503062

Risk of a new benzodiazepine prescription in relation to recent hospitalization. Keywords Mesh Terms:

KEYWORDS: Risk

MESH TERMS: statistics & numerical data

Chemical & Substance for Abstract: Risk of a new benzodiazepine prescription in relation to recent hospitalization. Information

Substance Name: Benzodiazepines

Registry Number: 0

Grant and Affiliation Information for Risk of a new benzodiazepine prescription in relation to recent hospitalization.

AFFILIATION: McGill University and the Royal Victoria Hospital, Montreal, Quebec.

Country: UNITED STATES

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MEDLINETA: J Am Geriatr Soc

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