Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501.

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Abstract Text:

Eiji Nomura,Mitsuru Sasako,Seiichiro Yamamoto,Takeshi Sano,Toshimasa Tsujinaka,Taira Kinoshita,Hiroshi Furukawa,Toshio Shimizu,Masahiro Hiratsuka,Osamu Kobayashi,Yukinori Kurokawa,Nobuhiko Tanigawa, ,

BACKGROUND: No risk factor has been confirmed for para-aortic lymph node (PAN) metastasis from gastric cancer. To identify the risk factors and the most frequent route of metastasis to PAN, we analyzed the prospective data from a phase III trial. METHODS: In JCOG9501 comparing D2 and D2 + PAN dissection, 260 patients with T2(SS)-T4 gastric cancer underwent radical gastrectomy with PAN dissection. The association between various clinicopathological factors and PAN metastasis was examined. RESULTS: Macroscopic N stage and tumor size > or = 5 cm were significant risk factors for PAN metastasis after adjusting for other factors. The proportion of PAN metastasis was clearly different between the N0-1 group and the N2-4 group (2.8% versus 20.5%). In the additional multivariate analysis including 17 regional lymph node stations, station No. 7 was the only station with statistical significance (P = 0.002, odds ratio = 41.0). CONCLUSION: Macroscopic N stage and tumor size were associated with PAN metastasis, and the lymphatics along the left gastric artery seemed to be the most frequent route to the nodes surrounding the aorta. These findings may be useful in predicting PAN metastasis.

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Publishing Authors By Initials

E Nomura,M Sasako,S Yamamoto,T Sano,T Tsujinaka,T Kinoshita,H Furukawa,T Shimizu,M Hiratsuka,O Kobayashi,Y Kurokawa,N Tanigawa, ,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Japanese journal of clinical oncology

VOLUME: 37

Page Numbers: 429-33

Journal Abbreviation: Jpn. J. Clin. Oncol.

ISSN: 1465-3621

DAY: 27

MONTH: Jun

YEAR: 2007

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 313225

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501.

AFFILIATION: Department of General and Gastroenterological Surgery, Osaka Medical College, Takatsuki, Osaka, Japan. sur035@poh.osaka-med.ac.jp

Country: Japan

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Jpn J Clin Oncol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501 Related Publications

• A silicon electrostatic ultrasonic transducer.
• Age-Period-Cohort Analysis of Mortality due to Ischemic Heart Disease in Japan, 1955 to 2000.
• Diffusion-weighed MR imaging of pancreatic carcinoma.
• Dual-phase 3D CT angiography during a single breath-hold using 16-MDCT: assessment of vascular anatomy before laparoscopic gastrectomy.
• Evaluation of combined docetaxel and nedaplatin chemotherapy for recurrent esophageal cancer compared with conventional chemotherapy using cisplatin and 5-fluorouracil: a retrospective study.
• Preoperative assessment of vascular anatomy around the stomach by 3D imaging using MDCT before laparoscopy-assisted gastrectomy.
• Proteomic analysis of the basic proteins in 5-fluorouracil resistance of human colon cancer cell line using the radical-free and highly reducing method of two-dimensional polyacrylamide gel electrophoresis.
• Proteomics-based identification of autoantibody against heat shock protein 70 as a diagnostic marker in esophageal squamous cell carcinoma.
• Risk factors for para-aortic lymph node metastasis of gastric cancer from a randomized controlled trial of JCOG9501.
• Video laryngoscopy for emergency tracheal intubation during chest compression.
• [Clinical effect and positioning of capecitabine for metastatic breast carcinoma.]
• [Three-dimensional transesophageal echocardiographic assessment for prosthetic valves]