Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge.

Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge. Research Abstract Details 

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Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge. Abstract Text:

Yoshiyuki Tokuda,Min-Ho Song,Norifumi Mabuchi,Akihiko Usui,Yuichi Ueda,Yoshiyuki Tokuda,Min-Ho Song,Norifumi Mabuchi,Akihiko Usui,Yuichi Ueda,

BACKGROUND: This study evaluated the right ventricular end-diastolic volume index (RVEDVI) as a marker of the hemodynamic response to a fluid challenge in the postoperative care of cardiac surgery patients. METHODS AND RESULTS: Continuous RVEDVI and other hemodynamic parameters were analyzed during and after 17 fluid challenges with 480-500 ml colloids (5% albumin, fresh frozen plasma or 6% hydroxyethyl starch) given over 30-60 min following cardiac surgery. Changes in stroke volume index (SVI) were assessed to indicate fluid responsiveness. Responders were defined as those who experienced a 10% or greater increase in SVI. Fluid challenges with simultaneous changing of vasoactive agents were excluded. Linear regression analysis between the percentage change in SVI and baseline RVEDVI revealed a statistically significant but weak correlation (r(2)=0.249; p=0.041). Although the baseline RVEDVI was higher in non-responders than in responders (112.4+/-6.1 vs 104.4+/-5.8 ml/m(2); p=0.05), there was a marked overlap of baseline RVEDVI values, which did not allow identification of the threshold value of RVEDVI discriminating responders. CONCLUSIONS: After cardiac surgery, RVEDVI reflected fluid responsiveness only to a limited degree. Patients should not be resuscitated to an absolute RVEDVI alone and empirical fluid challenge should still be required.

Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge. Publishing Authors By Initials

Y Tokuda,MH Song,N Mabuchi,A Usui,Y Ueda,Y Tokuda,MH Song,N Mabuchi,A Usui,Y Ueda,

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Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Circulation journal : official journal of the Japa

VOLUME: 71

Page Numbers: 1408-11

Journal Abbreviation: Circ. J.

ISSN: 1346-9843

DAY: 27

MONTH: Sep

YEAR: 2007

Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients: a marker of the hemodynamic response to a fluid challenge.

AFFILIATION: Department of Cardiovascular Surgery, Gifu Prefectural Tajimi Hospital, Tajimi, Japan. tokuda@mxb.mesh.ne.jp

Country: Japan

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MEDLINETA: Circ J

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