Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus.

Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Research Abstract Details 

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Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Abstract Text:

Yasuo Sumi,Kazuhiro Yagita,Shun Yamaguchi,Yoshiki Ishida,Yoshikazu Kuroda,Hitoshi Okamura,

The expression of the brain rich orphan nuclear receptor ROR beta (retinoid-related orphan receptor beta) was investigated in the mouse brain by in situ hybridization using antisense cRNA probe. Positive ROR beta mRNA signals were detected in various parts of the brain with high expression in the suprachiasmatic nucleus (SCN). In the SCN, ROR beta mRNA signals showed a peak at early daytime (ZT/CT4) and a trough at early nighttime (ZT/CT16) in both light-dark and constant dark conditions. Light exposure at subjective night did not alter the expression level. These findings suggest that ROR beta is a new member of a transcription factor possibly related to the circadian pacemaking system.

Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Publishing Authors By Initials

Y Sumi,K Yagita,S Yamaguchi,Y Ishida,Y Kuroda,H Okamura,

For similar genetic processes: gene expression regulation: up-regulation research abstracts see: genetic processes: gene expression regulation: up-regulation research

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Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Neuroscience letters

VOLUME: 320

Page Numbers: 13-6

Journal Abbreviation: Neurosci. Lett.

ISSN: 0304-3940

DAY: 1

MONTH: Mar

YEAR: 2002

Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Information

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LANGUAGE: eng

NlmUniqueID: 7600130

Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Keywords Mesh Terms:

KEYWORDS: Up-Regulation

MESH TERMS: physiology

Chemical & Substance for Abstract: Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Information

Substance Name: retinoic acid-related orphan receptor be

Registry Number: 0

Grant and Affiliation Information for Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus.

AFFILIATION: Division of Molecular Brain Science, Department of Brain Sciences, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

Country: Ireland

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MEDLINETA: Neurosci Lett

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