RGD nanodomains grafting onto titanium surface.

RGD nanodomains grafting onto titanium surface. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

RGD nanodomains grafting onto titanium surface. Abstract Text:

G Forget,L Latxague,V Heroguez,C Labrugere,M C Durrieu,G Forget,L Latxague,V ,C ,M C Durrieu,

Titanium alloys exhibit excellent biocompatibility and corrosion resistance in the body fluid and possess mechanical properties similar of the bones' properties. When the loss of osseous is important in osseous surgery, large biomaterials are implanted and should be accepted by the organism. For increasing the biomaterials biocompatibility, biological compounds can be linked or deposited on the material surface making them biologically active. In order to study the tissue-implant interaction and to favor osteoblast-adhesion onto titanium, our work deals with the grafting of cell-binding peptides containing the Arginine-Glycine-Aspartic acid (RGD) sequence. In the present study, we focus on the elaboration of patterned biomaterial surfaces with highly functionalized nanodomains. The strategy of RGD peptide immobilization involves first the grafting if an amino-functional organosilane (APTES). Then, each of the free amino moieties were used as an initiator core for a dendrimer-like synthesis to multiply the number of free groups available for RGD immobilization on the material surface.

RGD nanodomains grafting onto titanium surface. Publishing Authors By Initials

G Forget,L Latxague,V Heroguez,C Labrugere,MC Durrieu,G Forget,L Latxague,V ,C ,MC Durrieu,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

RGD nanodomains grafting onto titanium surface. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Conference proceedings : ... Annual International

VOLUME: 1

Page Numbers: 5107-10

Journal Abbreviation:

ISSN: 1557-170X

DAY: 16

MONTH: 11

YEAR: 2007

RGD nanodomains grafting onto titanium surface. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101243413

RGD nanodomains grafting onto titanium surface. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: RGD nanodomains grafting onto titanium surface. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for RGD nanodomains grafting onto titanium surface.

AFFILIATION: INSERM U577 laboratory, University of Bordeaux 1, Bordeaux, France. phone: +33-557571730; fax: +33-556900517; e-mail: guillaume.forget@bordeaux.inserm.fr.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Conf Proc IEEE Eng Med Biol So

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

RGD nanodomains grafting onto titanium surface Related Publications

• Picosecond ultrasonics signal in biological materials: Comparison between predictions and experiments.
• RGD nanodomains grafting onto titanium surface.
• RGD peptides grafting onto poly(ethylene terephthalate) with well controlled densities.
• [Electrosurgery]
• [Not Available.]