Revisiting posttransplant survival for hepatitis C virus recipients.

Revisiting posttransplant survival for hepatitis C virus recipients. Research Abstract Details 

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Revisiting posttransplant survival for hepatitis C virus recipients. Abstract Text:

Nyingi Kemmer,Tiffany E Kaiser,Victoria Zacharias,Michelle Secic,Guy W Neff,

Hepatitis C virus (HCV) is the most frequent indication for adult liver transplantation in Europe and United States. Posttransplantation HCV recurrence is universal and previous studies have reported a reduced survival in comparison to non-HCV recipients. We report the findings of a comparative survival analysis of adult recipients (n=12,434) with HCV from two eras using the United Network for Organ Sharing database. Cox regression modeling was used to compare both eras (A: 1994-1998 and B: 1999-2003). The 1-, 3-, and 5-year adjusted graft survivals for era A (n=5,215) and era B (n=7,519) were 80%, 69%, and 62% versus 84%, 72%, and 64%, respectively (P<0.001), whereas the 1-, 3-, and 5-year adjusted patient survivals were 86%, 77%, and 70% for era A versus 87%, 78%, and 70% for era B, respectively (P=0.79). This comparative analysis of posttransplant outcomes for HCV recipients suggests an improvement in graft survival in the latter years.

Revisiting posttransplant survival for hepatitis C virus recipients. Publishing Authors By Initials

N Kemmer,TE Kaiser,V Zacharias,M Secic,GW Neff,

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Revisiting posttransplant survival for hepatitis C virus recipients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Transplantation

VOLUME: 84

Page Numbers: 932-3

Journal Abbreviation: Transplantation

ISSN: 0041-1337

DAY: 15

MONTH: Oct

YEAR: 2007

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LANGUAGE: eng

NlmUniqueID: 132144

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AFFILIATION: Division of Digestive Diseases, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA. nyingi.kemmer@uc.edu

Country: United States

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MEDLINETA: Transplantation

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