Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals.

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals. Research Abstract Details 

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Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals. Abstract Text:

Ian A Sutherland,

Future challenges in the field of bioprocessing include developing new downstream processes for the purification and manufacture of protein-based medicines to relieve the predicted bottleneck that may occur as a result of increasingly high titers obtained from fermentation processes. This review considers recent developments in centrifugal liquid-liquid partition chromatography using aqueous two-phase solvent systems, a gentle host medium for biologicals, and the prospect for scale-up and eventual manufacture of high-value pharmaceutical products.

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals. Publishing Authors By Initials

IA Sutherland,

For similar investigative techniques: technology, pharmaceutical research abstracts see: investigative techniques: technology, pharmaceutical research

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Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in drug discovery & development

VOLUME: 10

Page Numbers: 540-9

Journal Abbreviation:

ISSN: 1367-6733

DAY: 26

MONTH: Sep

YEAR: 2007

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals. Information

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LANGUAGE: eng

NlmUniqueID: 100887519

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals. Keywords Mesh Terms:

KEYWORDS: Technology, Pharmaceutical

MESH TERMS: trends

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Grant and Affiliation Information for Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent systems: its scale-up and prospects for the future production of high-value biologicals.

AFFILIATION: Brunel Institute for Bioengineering, Brunel University, Uxbridge, UB8 3PH, UK. ian.sutherland@brunel.ac.uk

Country: England

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MEDLINETA: Curr Opin Drug Discov Devel

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