Reversible dementia and corresponding CSF alterations due to intraspinal lumbosacral metastasis of a prostate carcinoma.

Reversible dementia and corresponding CSF alterations due to intraspinal lumbosacral metastasis of a prostate carcinoma. Research Abstract Details 

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Reversible dementia and corresponding CSF alterations due to intraspinal lumbosacral metastasis of a prostate carcinoma. Abstract Text:

F Winkler,A Gschwendtner,D Theisen,A Peraud,A Straube,F Winkler,A Gschwendtner,D Theisen,A Peraud,A Straube,

We report, for the first time, how intraspinal carcinoma metastasis can cause reversible dementia accompanied by distinct cerebrospinal fluid (CSF) alterations. A 73-year-old male patient who suffered from rapidly progressive dementia and gait disturbance showed marked abnormalities of CSF tau protein, amyloid beta(1-42), and prostate-specific antigen. A lumbosacral, intraspinal metastasis from a prostate carcinoma was found, and after microsurgical removal, CSF alterations normalized and the clinical symptoms regressed. This case illustrates how malignant tumors can disturb brain function via indirect mechanisms.

Reversible dementia and corresponding CSF alterations due to intraspinal lumbosacral metastasis of a prostate carcinoma. Publishing Authors By Initials

F Winkler,A Gschwendtner,D Theisen,A Peraud,A Straube,F Winkler,A Gschwendtner,D Theisen,A Peraud,A Straube,

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Reversible dementia and corresponding CSF alterations due to intraspinal lumbosacral metastasis of a prostate carcinoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: European journal of neurology : the official journ

VOLUME: 14

Page Numbers: 1400-2

Journal Abbreviation: Eur. J. Neurol.

ISSN: 1468-1331

DAY: 26

MONTH: 09

YEAR: 2007

Reversible dementia and corresponding CSF alterations due to intraspinal lumbosacral metastasis of a prostate carcinoma. Information

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LANGUAGE: eng

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AFFILIATION: Department of Neurology, Ludwig-Maximilians University, Munich, Germany. frank.winkler@med.uni-muenchen.de

Country: England

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MEDLINETA: Eur J Neurol

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