Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung.

Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung. Research Abstract Details 

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Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung. Abstract Text:

Yasushi Yamato,Teruaki Koike,Katsuo Yoshiya,Hirohiko Shinohara,Shinichi Toyabe,

PURPOSE: The objectives of this study were to identify the clinicopathologic characteristics and prognostic factors of small (2 cm or less in diameter) adenocarcinomas, and furthermore to assess the acceptability of performing a limited pulmonary resection in such patients. METHODS: We retrospectively reviewed 523 cases of cT1N0M0 peripheral adenocarcinoma measuring 2 cm or less on diagnostic images treated by a complete resection between 1991 and 2004. RESULTS: The overall 5-year survival rate of the patients with small adenocarcinomas was 83.6%. Univariate and multivariate analyses identified an older age, male sex, wedge resection, advanced stage, and Noguchi classification of C, D, E, or F as independent prognostic factors that adversely affected overall survival. However, there were no significant differences in the survival according to surgical procedure in the patients whose tumors had a maximum diameter of 1.0 cm or less or in Noguchi type A and B cases. CONCLUSIONS: Age, sex, surgical procedure, p-stage, and Noguchi classification were independent prognostic factors for survival in patients with small adenocarcinomas. A segmentectomy is therefore considered to be an acceptable alternative to a lobectomy for adenocarcinomas of 2 cm or less in diameter. A wedge resection may be acceptable for tumors measuring 1 cm or less in diameter or Noguchi type A and B tumors.

Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung. Publishing Authors By Initials

Y Yamato,T Koike,K Yoshiya,H Shinohara,S Toyabe,

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Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Surgery today

VOLUME: 38

Page Numbers: 109-14

Journal Abbreviation: Surg. Today

ISSN: 0941-1291

DAY: 1

MONTH: 02

YEAR: 2008

Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung. Information

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LANGUAGE: eng

NlmUniqueID: 9204360

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AFFILIATION: Division of Chest Surgery, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Niigata, 951-8566, Japan.

Country: Japan

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MEDLINETA: Surg Today

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