Results of random drug testing in an adolescent substance abuse program.

Results of random drug testing in an adolescent substance abuse program. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Results of random drug testing in an adolescent substance abuse program. Abstract Text:

Sharon Levy,Lon Sherritt,Brigid L Vaughan,Matthew Germak,John R Knight,

OBJECTIVE: The objective of this study was to estimate from a random urine drug-testing program for adolescents the proportion of drug tests that are susceptible to interpretation errors. METHODS: This was a secondary analysis of a clinical database and chart review from an adolescent outpatient substance abuse program at a large children's hospital. We analyzed from 110 adolescent patients (13-21 years of age) all 710 urine drug test results that were collected between December 2002 and July 2005 and 85 original laboratory reports for tests that were collected between December 2002 and May 2006 and were confirmed positive for opioids. We calculated the percentage of tests that were too dilute to interpret (potential false-negatives) and the percentage of confirmed positive tests for oxycodone that did not result in a positive initial screen (potential false-negatives). We also reviewed clinical information to determine whether confirmed positive tests resulted from legitimate use of prescription or over-the-counter medication (potential false-positives). RESULTS: Of 710 drug tests, 40 negative tests were too dilute to interpret properly, and 45 of 217 positive tests resulted from prescription medication use for a total of 85 tests that were susceptible to error. Of the 85 confirmatory laboratory reports reviewed, 43 were positive for oxycodone, but only 16 of these had produced a positive opiate screen. CONCLUSIONS: Unless proper procedures are used in collecting, analyzing, and interpreting laboratory testing for drugs, there is a substantial risk for error.

Results of random drug testing in an adolescent substance abuse program. Publishing Authors By Initials

S Levy,L Sherritt,BL Vaughan,M Germak,JR Knight,

For similar geographic locations: americas: north america: united states research abstracts see: geographic locations: americas: north america: united states research

PUBMED ID PMID:

MEDLINE DATE:

Results of random drug testing in an adolescent substance abuse program. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Pediatrics

VOLUME: 119

Page Numbers: e843-8

Journal Abbreviation: Pediatrics

ISSN: 1098-4275

DAY: 3

MONTH: Apr

YEAR: 2007

Results of random drug testing in an adolescent substance abuse program. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376422

Results of random drug testing in an adolescent substance abuse program. Keywords Mesh Terms:

KEYWORDS: United States

MESH TERMS: therapy

Chemical & Substance for Abstract: Results of random drug testing in an adolescent substance abuse program. Information

Substance Name: Oxycodone

Registry Number: 76-42-6

Grant and Affiliation Information for Results of random drug testing in an adolescent substance abuse program.

AFFILIATION: Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.

Country: United States

AGENCY: United States NIDA

GRANT: R01 DA104553

ACRONYM: DA

MEDLINETA: Pediatrics

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Results of random drug testing in an adolescent substance abuse program Related Publications

• A comparison of frequency and time domain analyses of motor unit rate coding: 1662: board #152 may 30 2:00 PM - 3:30 PM.
• AIDS: A PCD pathology?
• Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.
• Application of multi-locus analytical methods to identify interacting loci in case-control studies.
• B lymphocyte deficiency in IgH-transgenic rabbits.
• Bone morphogenetic protein-6 enhances gonadotrophin-dependent progesterone and inhibin secretion and expression of mRNA transcripts encoding gonadotrophin receptors and inhibin/activin subunits in chicken granulosa cells.
• Educating the Veterinary Professional about Animal Welfare.
• Effect of chlortetracycline supplementation during prebreeding and early gestation on age at puberty, ovulation rate, embryo survival and fetal development in gilts.
• Enzymatic detection of beta-lactam antibiotics in pharmaceutical products.
• Eosinophils and skin: a new link on cell death.
• Global patterns in bacterial diversity.
• H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy.
• Ionic Contra-Viral Therapy (ICVT); a new approach to the treatment of DNA virus infections.
• Is there still a place for endotracheal adrenaline in neonatal resuscitation?
• Motor unit discharge behavior within phasic bursts from higher threshold motor units: 1666: board #156 may 30 2:00 PM - 3:30 PM.
• Motor unit recruitment and de-recruitment asymmetry increases with increased frequency of sinusoidal force modulation: 1668: board #158 may 30 2:00 PM - 3:30 PM.
• Neurobiology and mechanisms of antidepressant treatment response in anxiety.
• Pharmacology of vitamin E in the newborn.
• Prescription drug misuse: a growing national problem.
• QUANTITATIVE METHODS FOR MOSQUITO LARVAL SURVEYS.
• Quantitative and qualitative beta diversity measures lead to different insights into factors that structure microbial communities.
• RecA dimers serve as a functional unit for assembly of active nucleoprotein filaments.
• Relative distribution of plasma flow markers and red blood cells across BBB openings in acute cerebral ischemia.
• Results of random drug testing in an adolescent substance abuse program.
• Separations of hydrophobic synthetic peptides in counter-current chromatography.
• Spatio-temporal information analysis of event-related BOLD responses.
• Strategies for treatment-resistant depression.
• Suppression of B lymphopoiesis at a lymphoid progenitor stage in adult rabbits.
• The "Six T's": barriers to screening teens for substance abuse in primary care.
• The human Rad51 K133A mutant is functional for DNA double-strand break repair in human cells.