Resting state cortical connectivity reflected in EEG coherence in individuals with autism.

Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Research Abstract Details 

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Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Abstract Text:

Michael Murias,Sara J Webb,Jessica Greenson,Geraldine Dawson,

BACKGROUND: Theoretical conceptions of autism spectrum disorder (ASD) and experimental studies of cerebral blood flow suggest abnormalities in connections among distributed neural systems in ASD. METHODS: Functional connectivity was assessed with electroencephalographic coherence between pairs of electrodes in a high-density electrode array in narrow frequency bands among 18 adults with ASD and 18 control adults in an eyes closed resting state. RESULTS: In the theta (3-6 Hz) frequency range, locally elevated coherence was evident for the ASD group, especially within left hemisphere frontal and temporal regions. In the lower alpha range (8-10 Hz), globally reduced coherence was evident for the ASD group within frontal regions and between frontal and all other scalp regions. The ASD group exhibited significantly greater relative power between 3 and 6 Hz and 13-17 Hz and significantly less relative power between 9 and 10 Hz. CONCLUSIONS: Robust patterns of over- and under-connectivity are apparent at distinct spatial and temporal scales in ASD subjects in the eyes closed resting state.

Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Publishing Authors By Initials

M Murias,SJ Webb,J Greenson,G Dawson,

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Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Biological psychiatry

VOLUME: 62

Page Numbers: 270-3

Journal Abbreviation: Biol. Psychiatry

ISSN: 0006-3223

DAY: 6

MONTH: 03

YEAR: 2007

Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Information

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LANGUAGE: eng

NlmUniqueID: 213264

Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Keywords Mesh Terms:

KEYWORDS: Reference Values

MESH TERMS: physiology

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Grant and Affiliation Information for Resting state cortical connectivity reflected in EEG coherence in individuals with autism.

AFFILIATION: University of Washington Autism Center, Seattle, Washington 98195, USA. mmurias@u.washington.edu

Country: United States

AGENCY: United States NIMH

GRANT: U54MH066399

ACRONYM: MH

MEDLINETA: Biol Psychiatry

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