Responses to mild cold stress are predicted by different individual characteristics in young and older subjects.

Responses to mild cold stress are predicted by different individual characteristics in young and older subjects. Research Abstract Details 

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Responses to mild cold stress are predicted by different individual characteristics in young and older subjects. Abstract Text:

David W DeGroot,George Havenith,W Larry Kenney,

Older individuals' ability to maintain core temperature during cold stress is impaired; however, the relative importance of individual characteristics that influence this response are unknown. The purpose of this study was to determine the relative influence of individual characteristics on core temperature and tissue insulation (I(t)) during mild cold stress. Forty-two young (23 +/- 1 yr, range 18-30 yr) and 46 older (71 +/- 1 yr, range 65-89 yr) subjects, varying widely in muscularity, adiposity, and body size, underwent a transient cooling protocol during which esophageal temperature (T(es)) was measured continuously and I(t) was calculated using standard equations. Multiple-regression analyses were performed to determine predictors of T(es) and I(t), and standardized regression coefficients were analyzed to determine the relative influence of each predictor. Candidate predictors included age, sex, weight, body surface area, body surface area-to-mass ratio, sum of skinfolds, percent fat, appendicular skeletal muscle mass, and thyroid hormone concentrations (triiodothyronine, thyronine). The sum of skinfolds explained 67% (P < 0.01) of the T(es) variance in young subjects vs. 2% (P = 0.30) in older subjects. Conversely, appendicular skeletal muscle mass explained a greater portion of the variance in older subjects for both T(es) (older: 28%, P < 0.01; young: 8%, not significant) and I(t) (older: 46%, P < 0.01; young: 17%, P < 0.01). The T(es) residual variance was considerably larger in older subjects (59-72% vs. 14-42% in young subjects), possibly due to varying rates of physiological aging. These results suggest that the relative influence of individual characteristics changes with aging.

Responses to mild cold stress are predicted by different individual characteristics in young and older subjects. Publishing Authors By Initials

DW DeGroot,G Havenith,WL Kenney,

For similar pathological conditions, signs and symptoms: pathologic processes: stress research abstracts see: pathological conditions, signs and symptoms: pathologic processes: stress research

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Responses to mild cold stress are predicted by different individual characteristics in young and older subjects. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of applied physiology (Bethesda, Md. : 198

VOLUME: 101

Page Numbers: 1607-15

Journal Abbreviation: J. Appl. Physiol.

ISSN: 8750-7587

DAY: 3

MONTH: 08

YEAR: 2006

Responses to mild cold stress are predicted by different individual characteristics in young and older subjects. Information

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LANGUAGE: eng

NlmUniqueID: 8502536

Responses to mild cold stress are predicted by different individual characteristics in young and older subjects. Keywords Mesh Terms:

KEYWORDS: Stress

MESH TERMS: physiopathology

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Grant and Affiliation Information for Responses to mild cold stress are predicted by different individual characteristics in young and older subjects.

AFFILIATION: Intercollege Graduate Degree Program in Physiology and Noll Laboratory, Department of Kinesiology, Pennsylvania State University, University Park, Pennsylvania, USA. dwd141@psu.edu

Country: United States

AGENCY: United States NIA

GRANT: T32-AG-00048–28

ACRONYM: AG

MEDLINETA: J Appl Physiol

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