[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy]

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy] Research Abstract Details 

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[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy] Abstract Text:

N Barnils,E Mesa,S ,A Ferrer-Artola,J Arruga,N Barnils,E Mesa,S ,A Ferrer-Artola,J Arruga,

OBJECTIVE: To ascertain the efficacy of idebenone and multivitamin treatment in Leber's hereditary optic neuropathy (LHON). METHOD: Two patients diagnosed of unilateral LHON were treated with megadoses of idebenone, vitamin C and riboflavin for one year. They were examined clinically before, during and after treatment. RESULTS: No improvement of visual function was observed. Despite the idebenone treatment, in both cases the second eye became involved. CONCLUSIONS: Despite previous reports of visual recovery with idebenone in patients with LHON, our experience shows that an effective treatment for Leber's disease remains to be found.

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy] Publishing Authors By Initials

N Barnils,E Mesa,S ,A Ferrer-Artola,J Arruga,N Barnils,E Mesa,S ,A Ferrer-Artola,J Arruga,

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[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archivos de la Sociedad Española de Oftalmología

VOLUME: 82

Page Numbers: 377-80

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ISSN: 0365-6691

DAY: 18

MONTH: Jun

YEAR: 2007

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy] Information

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LANGUAGE: spa

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Grant and Affiliation Information for [Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy]

AFFILIATION: Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. noebg76@hotmail.com

Country: Spain

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MEDLINETA: Arch Soc Esp Oftalmol

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