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Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults.

Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Research Abstract Details 

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  • Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Abstract Text:

    heather k vincentHeather K Vincent,cheryl bourguignonCheryl Bourguignon,kevin r vincentKevin R Vincent,heather k vincentHeather K Vincent,cheryl bourguignonCheryl Bourguignon,kevin r vincentKevin R Vincent,

    OBJECTIVE: To compare exercise-induced oxidative stress and levels of homocysteine and cholesterol in normal-weight and overweight older adults after resistance exercise (RX). RESEARCH METHODS AND PROCEDURES: This interventional study was conducted at a wellness center. Forty-nine older adults (age range, 60 to 72 years) were stratified by BMI (<25 kg/m(2) normal weight, > or =25 kg/m(2) overweight/obese) and then randomly assigned to either a control non-exercise group or an RX group. The RX group completed a 6-month training program. Exercise-induced lipid hydroperoxides (PEROXs) and thiobarbituric-reactive acid substances, homocysteine, lipoprotein a, cholesterol, and high-density lipoprotein cholesterol were measured before and after the 6-month RX program. RESULTS: PEROXs and thiobarbituric-reactive acid substances were lower in both the overweight/obese and normal-weight RX-trained groups compared with control groups (p < 0.05). Homocysteine levels were lower in both overweight/obese and normal-weight RX groups compared with control groups (p < 0.05). Lipoprotein a, total cholesterol, and high-density lipoprotein cholesterol were not different in normal-weight and overweight/obese groups before or after RX. The change in muscle strength was correlated with homocysteine at 6 months (r = -0.452, p < 0.05), whereas the change in PEROXs was correlated with the change in body fat (r = -0.329). DISCUSSION: To our knowledge, these data are the first to show that RX reduces exercise-induced oxidative stress and homocysteine regardless of adiposity, indicating that this protection can be afforded in an older, overweight/obese population as effectively as in healthy older adults. These data suggest that RX may afford some protection against emerging cardiovascular risk factors using a mode of exercise that supports body weight.

    Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Publishing Authors By Initials

    hk vincentHK Vincent,c bourguignonC Bourguignon,kr vincentKR Vincent,hk vincentHK Vincent,c bourguignonC Bourguignon,kr vincentKR Vincent,

    For similar human activities: leisure activities: recreation: sports: weight lifting research abstracts see: human activities: leisure activities: recreation: sports: weight lifting research

    PUBMED ID PMID:

    MEDLINE DATE:

    Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Journal Published:

    PUBLICATION TYPE: Research Support, N.I.H., Extr

    Journal: Obesity (Silver Spring, Md.)

    VOLUME: 14

    Page Numbers: 1921-30

    Journal Abbreviation:

    ISSN: 1930-7381

    DAY: 3

    MONTH: Nov

    YEAR: 2006

    Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 101264860

    Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Keywords Mesh Terms:

    KEYWORDS: Weight Lifting

    MESH TERMS: physiology

    Chemical & Substance for Abstract: Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Information

    Substance Name: Cholesterol

    Registry Number: 57-88-5

    Grant and Affiliation Information for Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults.

    AFFILIATION: Center for the Study of Complementary and Alternative Therapies, University of Virginia Health System, Charlottesville, VA, USA. hvincent@adelphia.net

    Country: United States

    United States Research PublicationUnited States Research Publication

    AGENCY: United States NCCAM

    GRANT: T32-AT00052

    ACRONYM: AT

    MEDLINETA: Obesity (Silver Spring)

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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