Research on expression of telomerase in human odontogenic lesions.

Research on expression of telomerase in human odontogenic lesions. Research Abstract Details 

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Research on expression of telomerase in human odontogenic lesions. Abstract Text:

Ming Zhong,Jie Wang,Youping Han,Zhaoyuan Wang,

OBJECTIVE: To study hTERT mRNA expression in ameloblastoma (AB) and odontogenic keratocyst (OKC) and to investigate genesis, development and biological characteristics of AB and OKC. METHODS: hTERT mRNA expression in 54 cases of AB, 16 cases of OKC, 7 cases of oral normal mucosa was detected by in situ hybridization. RESULTS: The positive rates of hTERT mRNA in AB, OKC, and oral normal mucosa were 94.4% (51/54), 87.5% (14/16), 1/7, respectively. There was significant statistical difference (P < 0.001). About clinicalpathology of AB, there was no difference for hTERT expression (P > 0.05) hTERT mRNA was positive in peripheral and stellate reticula cells. CONCLUSIONS: (1) hTERT activity plays an important role in genesis, development of AB. (2) hTERT positive rate is related to cell differentiation and clinical biological behavior.

Research on expression of telomerase in human odontogenic lesions. Publishing Authors By Initials

M Zhong,J Wang,Y Han,Z Wang,

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Research on expression of telomerase in human odontogenic lesions. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqia

VOLUME: 37

Page Numbers: 257-9

Journal Abbreviation: Zhonghua Kou Qiang Yi Xue Za Z

ISSN: 1002-0098

DAY: 4

MONTH: Jul

YEAR: 2002

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LANGUAGE: eng

NlmUniqueID: 8711066

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Grant and Affiliation Information for Research on expression of telomerase in human odontogenic lesions.

AFFILIATION: Department of Pathology, College of Stomatology, China Medical University, Shenyang 110002, China.

Country: China

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MEDLINETA: Zhonghua Kou Qiang Yi Xue Za Z

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