[Research of antioxidant defence system under alimentary induced oxidative stress]

[Research of antioxidant defence system under alimentary induced oxidative stress] Research Abstract Details 

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[Research of antioxidant defence system under alimentary induced oxidative stress] Abstract Text:

Iu V Kravchenko,G Iu Mal'tsev,A V Vasil'ev,

Alimentary induced oxidative stress and its corrections in children and adults with homocysteine metabolism disorder are urgent problems for arteriosclerosis and cardiovascular disease prophylactics. For determination antioxidant status GSH-Px, SOD, GSH-reductase, catalase activities were detected. Effectiveness of Se-contained antioxidant complex "Selenec" was determined in experimental model with pubertal male Wistar rats. Including high value of methionine to semipurified diet with pyridoxine and folate deficiency induced oxidative stress. Lipid peroxidation substances were increased in blood, liver, intestine mucous tunic, aortal endothelium and myocardium. GSH-Px, SOD, GSH-reductase, catalase activities decreased significant compared to control. "Selenec" supplementation caused a decrease of thiobarbituric-reactive substances level, increasing SOD and catalase activity and decreasing GSH-Px and GSH-reductase activity in blood, liver, intestine mucous tunic, aorta and myocardium.

[Research of antioxidant defence system under alimentary induced oxidative stress] Publishing Authors By Initials

IuV Kravchenko,GIu Mal'tsev,AV Vasil'ev,

For similar organic chemicals: aldehydes: malondialdehyde: thiobarbituric acid reactive substances research abstracts see: organic chemicals: aldehydes: malondialdehyde: thiobarbituric acid reactive substances research

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MEDLINE DATE:

[Research of antioxidant defence system under alimentary induced oxidative stress] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biomedit?sinskai?a khimii?a

VOLUME: 50

Page Numbers: 477-83

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ISSN:

DAY: 3

MONTH: 04

YEAR: 2008

[Research of antioxidant defence system under alimentary induced oxidative stress] Information

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LANGUAGE: rus

NlmUniqueID: 101196966

[Research of antioxidant defence system under alimentary induced oxidative stress] Keywords Mesh Terms:

KEYWORDS: Thiobarbituric Acid Reactive Substances

MESH TERMS: metabolism

Chemical & Substance for Abstract: [Research of antioxidant defence system under alimentary induced oxidative stress] Information

Substance Name: Glutathione Reductase

Registry Number: EC 1.8.1.7

Grant and Affiliation Information for [Research of antioxidant defence system under alimentary induced oxidative stress]

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Country: Russia

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MEDLINETA: Biomed Khim

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